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Acceptability, feasibility, and effectiveness of internet-based cognitive behavior therapy for obsessive-compulsive disorder (OCD-NET): a naturalistic pilot trial during the COVID-19 pandemic in a psychiatric outpatient department in Germany.
BMC Psychiatry
January 2025
Department of Psychiatry and Psychotherapy, Medical Faculty, Leipzig University, Leipzig, Germany.
Background: Cognitive behavior therapy (CBT) is the gold-standard treatment for obsessive-compulsive disorder (OCD). However, access to CBT and specialized treatments is often limited. This pilot study describes the implementation of a guided Internet-Based CBT program (ICBT) for individuals seeking treatment for OCD in a psychiatric outpatient department in Leipzig, Germany, during the COVID-19 pandemic.
View Article and Find Full Text PDFAmphibian cellular immune response to chytridiomycosis at metamorphic climax.
Immunol Res
January 2025
School of Environment and Science, Griffith University, Southport, QLD, 4222, Australia.
The fungal disease chytridiomycosis (caused by Batrachochytrium dendrobatidis [Bd]) is a primary contributor to amphibian declines. The frog metamorphic stages, characterised by extensive physiological reorganisation and energy expenditure, have heightened susceptibility to Bd. However, little is known about how these metamorphic stages respond immunologically to Bd infection.
View Article and Find Full Text PDFRisk of long covid in patients with pre-existing chronic respiratory diseases: a systematic review and meta-analysis.
BMJ Open Respir Res
January 2025
Department of Medicine, The University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, USA
Background: An estimated 10-30% of people with COVID-19 experience debilitating long-term symptoms or long covid. Underlying health conditions associated with chronic inflammation may increase the risk of long covid.
Methods: We conducted a systematic review and meta-analysis to examine whether long covid risk was altered by pre-existing asthma or chronic obstructive pulmonary disease (COPD) in adults.
High-Throughput Zebrafish Screening Reveals Cardiotoxic Effects of Organophosphate Flame Retardants.
Environ Res
January 2025
International Research Center for Marine Biosciences, Shanghai Ocean University, Ministry of Science and Technology, Shanghai 201306, P.R. China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Science and Technology, Shanghai Ocean University, Shanghai 201306, P.R. China; Marine Biomedical Science and Technology Innovation Platform of Lin-gang Special Area, Shanghai 201306, P.R. China. Electronic address:
The toxicity of organophosphorus flame retardants (OPFRs) remains poorly understood, despite their widespread environmental presence and potential risks to human and ecological health. This study aimed to characterize the cardiovascular developmental toxicity of OPFRs using a high-throughput zebrafish screening model. Over thirty representative OPFRs, classified into three major groups-alkyl, aryl, and halogenated-were evaluated.
View Article and Find Full Text PDFThe prevalence and outcomes of viremia in patients with acute respiratory viral infection: a systematic review and meta-analysis.
Clin Microbiol Infect
January 2025
National Center for Respiratory Medicine Beijing, PR China; State Key Laboratory of Respiratory Health and Multimorbidity, Beijing, PR China; National Clinical Research Center for Respiratory Diseases, Beijing, PR China; Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Beijing, PR China; Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, PR China; Changping Laboratory, Beijing, PR China; Department of Pulmonary and Critical Care Medicine, Capital Medical University, Beijing, PR China; Tsinghua University-Peking University Joint Center for Life Sciences, Beijing, PR China. Electronic address:
Background: Viremia has been detected in a significant proportion of patients with acute respiratory viral infection, yet its clinical value remains underappreciated.
Objectives: This study synthesized available evidence to comprehensively assess the prevalence of viremia and its impact on clinical outcomes.
Data Sources: Data were retrieved from Medline (via Ovid), Embase, and the WHO COVID-19 database.
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