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Gastric glomus tumor with uncertain malignant potential: case report of a rare cause of upper gastrointestinal bleeding.

World J Surg Oncol

November 2024

Department of Surgery, Albert Szent-Györgyi Health Center, University of Szeged, Semmelweis Street 8, Szeged, H-6725, Hungary.

Article Synopsis
  • Glomus tumors (GTs) are mostly benign neoplasms found in the upper gastrointestinal tract, making malignant cases exceptionally rare, which complicates diagnosis due to similarities with other tumors.
  • A 52-year-old male patient experienced fatigue and bleeding, leading to the discovery of a gastric GT after multiple examinations, with histopathology confirming it as a potentially malignant tumor.
  • The case highlights the need for detailed histopathological and molecular analysis for correct diagnosis and stresses the importance of surgical intervention and long-term monitoring for recurrence and malignancy risks.
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Background: Leiomyomas are benign smooth muscle tumors found at the gastroesophageal junction (GEJ) ( Mathew G, Osueni A, Carter YM. Esophageal Leiomyoma. StatPearls.

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Objective: To investigate the effect of edible bird's nest (EBN) on tumor growth, hemorheology and immune function of mice with transplanted uterine myomas.

Methods: A subcutaneous tumor model of human uterus myoma was established in mice, and the mice were randomly divided into a model group, EBN group, estradiol receptor (ER) group and ER+EBN group. Body weight and tumor volume were measured at 2 weeks, 4 weeks and 8 weeks after the uterus myoma transplantation.

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Article Synopsis
  • A study was conducted to evaluate the safety and effectiveness of endoscopic submucosal dissection using a clutch cutter (ESD-CC) for removing subepithelial lesions in the esophagogastric area.
  • The research involved 15 patients with 18 lesions, showing a high en bloc resection rate of 94.4% and an R0 resection rate of 88.9%, with no major complications reported during the procedure.
  • The final diagnoses included various types of tumors, indicating that ESD-CC could be a promising and safe treatment option for these specific lesions.
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