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Insights and Opportunities from Multimarker Evaluation of Heart Failure: Lessons from BIOSTAT-HF.
Curr Heart Fail Rep
January 2025
Division of Cardiovascular Medicine, Department of Medicine, University of California, 9394 Medical Center Drive, La Jolla, San Diego, CA, USA.
Purpose Of Review: Heart failure is a complex and heterogenous disease state that affects millions worldwide. Over recent decades, advancements in medical therapy and device implementation have significantly transformed the landscape of heart failure outcomes, while improvements in imaging modalities and greater accessibility to genome sequencing have led to increasing recognition of distinct heart failure endotypes. There is rising evidence to suggest all patients do not benefit equally from intensification of guideline directed medical therapy (GDMT).
View Article and Find Full Text PDFWarning people that they are being microtargeted fails to eliminate persuasive advantage.
Commun Psychol
January 2025
School of Psychological Science, University of Bristol, Bristol, UK.
The practice of microtargeting in politics, involving tailoring persuasive messages to individuals based on personal vulnerabilities, has raised manipulation concerns. As microtargeting's persuasive benefits are well-established and its use facilitated by AI tools and personality-inference models, ethical and regulatory concerns are magnified. Here, we explore countering microtargeting effects by creating a warning signal deployed when users encounter personality-tailored political ads.
View Article and Find Full Text PDFAdvances in personalized medicine and Systems Biology have introduced probabilistic models and error discovery to cardiovascular care, aiding disease prevention and procedural planning. However, clinical application faces cultural, technical, and methodological hurdles. Patient autonomy remains essential, with shared decision-making (SDM) gaining importance in managing complex cardiovascular treatment options.
View Article and Find Full Text PDFNursing team proxemic mapping in the hemotherapy space.
Rev Esc Enferm USP
January 2025
Universidade Federal do Rio de Janeiro, Escola de Enfermagem Anna Nery, Departamento de Enfermagem Médico-Cirúrgica, Rio de Janeiro, RJ, Brazil.
Objective: To analyze the influence of proxemic factors on communication and care provided by nursing professionals during transfusion in hemotherapy.
Method: A descriptive, exploratory and qualitative study with 25 nursing professionals from a hospital specializing in onco-hematological diseases in Rio de Janeiro, based on a systematized script, individual records of proxemic factors described by Edward Hall and recorded situational interviews. The analysis considered data thematic content and used the SketchUp 3D Modeling Software Review program to visually demonstrate the behavioral mapping of the interaction of nursing professionals with patients during care.
Trends and Disparities in Intrahepatic Cholangiocarcinoma-related Mortality in the United States from 1999 to 2020.
J Gastrointest Cancer
January 2025
Department of Internal Medicine, UCHealth Parkview Medical Center, Pueblo, CO, USA.
Purpose: Intrahepatic cholangiocarcinoma (ICC) arises from the epithelial cells of the bile ducts present inside the liver parenchyma and is associated with an overall poor prognosis due to advanced disease stage at the time of diagnosis. We used the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database to determine ICC-related mortality patterns in the United States from 1999 till 2020.
Methods: Age-adjusted mortality rates (AAMR) and crude mortality rates (CMR) were extracted from the CDC WONDER database.
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