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Optimized PCF architectures for THz detection of aquatic pathogens: Enhancing water quality monitoring.
PLoS One
January 2025
Department of Electrical and Electronic Engineering, Pabna University of Science and Technology, Pabna, Bangladesh.
Waterborne bacteria pose a serious hazard to human health, hence a precise detection method is required to identify them. A photonic crystal fiber sensor that takes into account the dangers of aquatic bacteria has been suggested, and its optical characteristics in the THz range have been quantitatively assessed. The PCF sensor was designed and examined as computed in Comsol Multiphysics, a program in which uses the method of "Finite Element Method" (FEM).
View Article and Find Full Text PDFTargeting murine metastatic cancers with cholera toxin A1-adjuvanted peptide vaccines.
Hum Vaccin Immunother
December 2025
TIMM Laboratory, Sahlgrenska Center for Cancer Research, Department of Microbiology and Immunology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
The dissemination of tumor cells with ensuing metastasis is responsible for most cancer-related deaths. Cancer vaccines may, by inducing tumor-specific effector T cells, offer a strategy to eliminate metastasizing tumor cells. However, several obstacles remain in the development of effective cancer vaccines, including the identification of adjuvants that enhance the evolvement and efficacy of tumor-specific T cells.
View Article and Find Full Text PDFExploring the burden of cholera in the WHO African region: patterns and trends from 2000 to 2023 cholera outbreak data.
BMJ Glob Health
January 2025
Emergency Preparedness and Response Programme, Brazzaville, Congo.
Introduction: Cholera outbreaks remain persistent in the WHO African region, with an increased trend in recent years. This study analyses actual drivers of cholera including correlations with water, sanitation, and hygiene (WASH) indicators, and climate change trends.
Methods: This was a cross-sectional descriptive and analytic study.
An assessment of the progress made in the implementation of the regional framework for cholera prevention and control in the WHO African region.
BMJ Glob Health
January 2025
Emergency Preparedness and Response, WHO Regional Office for Africa, Brazzaville, Congo.
High-burden cholera outbreaks, spreading beyond the traditional cholera-endemic countries, have been reported since 2021 in the WHO African region. Member states in the region have committed to the global goal of cholera elimination by 2030. To track progress towards this goal, WHO-African countries adopted a regional cholera prevention and control framework in 2018.
View Article and Find Full Text PDFMachine Learning Potential for Identifying and Forecasting Complex Environmental Drivers of Infections in the United States.
Environ Health Perspect
January 2025
Centre for Environment, Fisheries and Aquaculture Science (CEFAS), Weymouth, UK.
Background: Environmental change in coastal areas can drive marine bacteria and resulting infections, such as those caused by , with both foodborne and nonfoodborne exposure routes and high mortality. Although ecological drivers of in the environment have been well-characterized, fewer models have been able to apply this to human infection risk due to limited surveillance.
Objectives: The Cholera and Other Illness Surveillance (COVIS) system database has reported infections in the United States since 1988, offering a unique opportunity to both explore the forecasting capabilities machine learning could provide and to characterize complex environmental drivers of infections.
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