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In Light of the LANDI-SEP Trial: New Evidence or Double Jeopardy?
Indian J Crit Care Med
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Department of Critical Care Medicine, Ruby Hall Hospital, Pune, Maharashtra, India.
Datta PK, Sathe P, Bhattacharjee A, Kundu R. In Light of the LANDI-SEP Trial: New Evidence or Double Jeopardy? Indian J Crit Care Med 2025;29(1):84-85.
View Article and Find Full Text PDFThe Clinical Utility of Targeted Heart Rate Control in Septic Shock: A Systematic Review and Meta-analysis of Randomized Controlled Trials with Trial Sequential Analysis.
Indian J Crit Care Med
December 2024
Department of Critical Care Medicine, Ruby Hall Hospital, Pune, Maharashtra, India.
Objectives: Heart rate control using beta-blockers in sepsis has traditionally been avoided because of concerns with worsening cardiac index and organ perfusion. Recent studies has explored the possible beneficial effects of targeted heart rate control in patients with septic shock who have tachycardia despite initial resuscitation. We performed a systematic review and meta-analysis to explore the effects of heart rate control in septic shock patients.
View Article and Find Full Text PDFIMPACT OF NOCTURNAL OXYGEN ENRICHMENT ON HIGH-ALTITUDE ACCLIMATIZATION.
Am J Physiol Regul Integr Comp Physiol
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School of Integrative Physiology and Athletic Training, Montana Center for Work Physiology and Exercise Metabolism, University of Montana, Missoula, MT, USA.
Nocturnal oxygen enrichment improves sleep at high-altitude but may impair acclimatization. Determine if nocturnal oxygen enrichment impacts acclimatization. A 7-day acclimatization protocol occurred at a field-based research site between 0-4200m.
View Article and Find Full Text PDFReverse saturation of absorption is a relatively rare phenomenon in light-matter interaction, as it requires a few conditions to be fulfilled. We observe that ruby exhibits a very strong reverse saturation of absorption at 473 nm. Furthermore, we measure the group velocity of a modulated laser beam in ruby and observe that the peaks of the pulses appear more than a hundred microseconds earlier than the reference signal.
View Article and Find Full Text PDFTorsemide as a Primary Choice in Edema Associated with Heart Failure.
J Assoc Physicians India
September 2024
Cluster Medical Head, Medical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.
Heart failure (HF) is the fastest-growing disease with a higher fatality rate. The most differentiating feature of HF is pulmonary or peripheral edema, which is characterized by a gradient between intravascular and extravascular pressure. Loop diuretics were chosen as the primary treatment for edema associated with HF due to their efficacy and early onset of action.
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