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The accuracy and reliability of the immunochemical tube test Gravinep for the early pregnancy detection were determined in comparison with another immunochemical test (Pregnosticon All-in) and with clinical data. The urine samples of 88 women were analysed. In 98.

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A kit for home testing for pregnancy (Predictor) was tested by 201 volunteers with a menstrual delay of eight days or more who had requested a pregnancy test at a pharmacy. This number corresponds to two-thirds of the women attending the pharmacy for this purpose during the study period. The same urine sample was also tested by experienced analysts with Pregnosticon All-In--an essentially identical method with a guaranteed sensitivity of 1000 U/1 (2nd IS)--as well as assayed for choriogonadotrophin (CG) content by a sensitive and specific radioimmunoassay.

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A simple, sensitive, and reliable single-unit nonradioactive method for the detection of human chorionic gonadotropin (hCG) in concentrated urine and the diagnosis of early pregnancy is reported. This unit, presently termed the Ayerst pregnancy test kit (APTK), consists of four components: a sampler-filter paper cone, an ultrafilter-concentrator to which a vial holder is attached, a support stand with a mirror, and an immunologic reagent vial. In the APTK, 5 to 6 ml of urine were sampled, filtered, and concentrated, and the hCG in the retentate was detected by Ayerst immunologic reagents [APTK(AY)] and by the Pregnosticon "All In" [APTK(P)].

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