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Use of isavuconazole in mucormycosis: a systematic review.
BMC Infect Dis
January 2025
Department of Microbiology Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura Sri Lanka, 50008, Sri Lanka.
Background: Mucormycosis is an opportunistic fungal infection which is associated with poor prognosis. Only a few antifungals are available in the arsenal against mucormycosis. The global guidelines for diagnosing and managing mucormycosis recommend high doses of liposomal amphotericin B (LAmB) as the first-line treatment.
View Article and Find Full Text PDFRhino-orbital-cerebral mucormycosis in acute myeloid leukemia patients: a case series from Sri Lanka.
BMC Infect Dis
December 2024
National Cancer Institute, Maharagama, Sri Lanka.
Background: Mucormycosis, is a rare yet potentially life-threatening fungal infection common in immunocompromised patients. Despite optimal care, mucormycosis in haemato-oncological patients often results in poor outcomes. This case series details the presentations and unique challenges faced during the management of patients with acute myeloid leukemia who developed rhino-cerebral mucormycosis.
View Article and Find Full Text PDFMucormycosis after liver transplant: Case series and literature review.
Med Mycol Case Rep
December 2024
Infectious Diseases Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Colonia Belisario Domíngeuz Sexxión XVI, Tlalpan, Mexico City, CP 4080, Mexico.
Article Synopsis
- Two liver transplant recipients developed possible healthcare-associated mucormycosis, a serious fungal infection.
- Mucorales fungi can be acquired from contaminated medical equipment and procedures, making it a concern in clinical settings.
- Early diagnosis and treatment, including antifungal medications and surgery, are crucial for improving survival rates due to the high mortality associated with this infection.
Role of myeloid-derived suppressor and Th17/Treg cells in post-COVID-19 Rhino-Orbital mucormycosis cases.
Immunopharmacol Immunotoxicol
February 2025
College of Nursing and Health Sciences, Jazan University, Jazan, Saudi Arabia.
Rhino-Orbital-Cerebral Mucormycosis (ROCM) cases increased sharply in India during the second COVID-19 wave. Due to uncontrolled hyperglycemia, prolonged steroid use, and high ferritin levels, the immune system was dysregulated throughout this surge. Our study examined post-COVID-19 ROCM patients' T regulatory cell (Treg), T helper 17 cell (Th17) and Myeloid derived suppressor cell (MDSC) levels before and after three months of treatment.
View Article and Find Full Text PDFUnusual Presentation of Conidiobolomycosis.
J Assoc Physicians India
December 2024
Assistant Professor, St John's Medical College, Bengaluru, Karnataka, India, Corresponding Author.
A 31-year-old gentleman, hailing from West Bengal, a farmer by occupation, with no known prior comorbidities, presented with a history of multiple painful swellings over the abdomen, thorax (back and front), and suprapubic region of 6 months' duration. The swelling started in the abdomen and subsequently involved the thorax. It also progressively increased in size over the 6 months.
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