Authors ten years experience and results in the surgical treatment of the gastroduodenal ulcer on Surgical clinic "Dr. M.Stojanovic" in Zagreb is esposed. During this period 1226 patients with the gastroduodenal ulcer operated, 804 from them with chronic, and 422 with acute complications as are perforation and bleeding. On the first period of time patients with the duodenal ulcer were operated by combined operative methods selective gastric vagotomy and antrectomy, and after 1975 by PSV with or without drainage procedure depent of the passage of the duodenum. The most of the patients with the gastric ulcer were operated by the Billroth I method of resection. PSV with suture of the perforated or bleeding ulcer of the duodenum is recommanded. 200 patients with chronic or acute complicated ulcer were operated by PSV with no death complication. All patients are normally tested before operation and 3 months, 12 months, and every year after operation. The results achieved by this method of the surgical treatment of the gastroduodenal ulcer are satisfied and harmonize with the modern therapy of ulcer disease.
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JAMA Surg
January 2025
Department of Surgery, State University of New York, Downstate Health Sciences University, Brooklyn.
Importance: Chronic limb-threatening ischemia (CLTI) is a major public health issue that requires considerable human and physical resources to provide optimal patient care. It is essential to characterize the disease severity and resource needs of patients with CLTI presenting to facilities of varying resource capacities.
Objective: To investigate the association between facility-level Medicaid payer proportions and the incidence of nonelective admissions among patients admitted for CLTI.
Adv Exp Med Biol
January 2025
Department of Optometry, University of Benin, Benin City, Nigeria.
Contact lenses have become integral tools in the realm of ocular therapeutics, extending beyond their primary function of refractive correction to encompass a diverse array of therapeutic applications. This review explores the evolving role of contact lenses in managing various ocular conditions, highlighting their efficacy in enhancing patient outcomes. Initially developed to correct refractive errors, contact lenses now serve as effective vehicles for delivering medications directly to the ocular surface, offering targeted treatment for conditions such as dry eye syndrome and corneal ulcers.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
January 2025
The First Clinical College of Medicine, Fujian Medical University, Fuzhou, 350005, China.
Ulcerative colitis (UC) remains an intractable and relapsing disease featured by intestinal inflammation. The anti-UC activity of Akkermansia muciniphila (AKK), an intestinal microorganism, has been widely investigated. The current work is to explore the impacts of AKK on UC and its possible reaction mechanism.
View Article and Find Full Text PDFBJS Open
December 2024
Department of Abdominal Surgery, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Background: Proctocolectomy with ileal pouch-anal anastomosis is the treatment of choice for patients with ulcerative colitis with medical refractory disease or dysplasia. The aim of this research was to describe the evolution of ileal pouch-anal anastomosis surgery and surgical outcomes over a three-decade interval in a high-volume referral centre.
Methods: All consecutive patients undergoing ileal pouch-anal anastomosis for ulcerative colitis between 1990 and 2022 at the University Hospitals of Leuven were retrospectively included.
Front Pharmacol
January 2025
Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Introduction: Preventive drugs for stress ulcers are widely and unreasonably used in the Intensive Care Unit (ICU). This study aims to examine the appropriate utilization of medications for stress ulcer prophylaxis (SUP) and identify factors that contribute to the inappropriate use of these medications in the ICU of the Second Hospital of Shanxi Medical University.
Methods: Patient cases admitted to the ICU during the period from May 2022 to May 2023 were extracted from the hospital's information management system.
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