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Application of machine learning methods for predicting esophageal variceal bleeding in patients with cirrhosis.
Eur Radiol
December 2024
Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Objective: To develop and compare machine learning models based on CT morphology features, serum biomarkers, and basic physical conditions to predict esophageal variceal bleeding.
Materials And Methods: Two hundred twenty-four cirrhotic patients with esophageal variceal bleeding and non-bleeding were included in the retrospective study. Clinical and serum biomarkers were used in our study.
Prevalence, Incidence, and Treatment Pattern of Wilson's Disease Using National Health Insurance Data From 2010-2020, Korea.
J Korean Med Sci
April 2024
Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Background: Wilson's disease (WD) is an autosomal recessive disorder in which copper (Cu) accumulates in organs, particularly in the liver and central nervous system. This study aimed to investigate the prevalence, incidence, and treatment patterns of WD patients in Korea.
Methods: National Health Insurance System (NHIS) claims data from 2010 to 2020 were analyzed.
Diagnostic criteria for acute-on-chronic liver failure and related disease conditions in Japan.
Hepatol Res
May 2022
Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan.
The Intractable Hepato-Biliary Disease Study Group of Japan, sponsored by the Ministry of Health, Labor and Wealth, proposed in 2018 that patients with cirrhosis and a Child-Pugh score of 5-9 should be diagnosed as having acute-on-chronic liver failure (ACLF) when a deterioration of liver function ("serum bilirubin level of 5.0 mg/dl or more" and "prothrombin time value of 40% or less of the standardized values and/or international normalization rates of 1.5 or more") caused by severe liver damage develops within 28 days after an acute insult, including alcohol abuse, bacterial infection, gastrointestinal bleeding, and the exacerbation of underlying liver diseases.
View Article and Find Full Text PDFRescue fibrin glue-infiltrating hemostasis combined with hepatorrhaphy to control intractable postoperative bleeding from the liver cut surface.
Ann Hepatobiliary Pancreat Surg
November 2021
Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Various topical hemostatic agents can help induce coagulation at the liver cut surface. However, hemostasis is usually ineffective in controlling bleeding. We present a case of rescue fibrin glue-infiltrating hemostasis combined with hepatorrhaphy to manage intractable postoperative bleeding from the liver cut surface.
View Article and Find Full Text PDF[Second-line therapy with mycophenolate mofetil in patients with autoimmune hepatitis who were intolerant or failed to respond to standard treatment].
Nihon Shokakibyo Gakkai Zasshi
April 2021
Department of Medicine, Teikyo University School of Medicine.
Although standard treatment for autoimmune hepatitis (AIH) comprises prednisolone (PSL) and azathioprine (AZA), some patients are intolerant to or do not respond to PSL and/or AZA. The clinical practice guidelines of AIH in Europe and North America recommend mycophenolate mofetil (MMF) as second-line treatment in these patients. We administered MMF as second-line therapy to 7 patients with AIH (male/female 1/6, age range 27-79 years) who were intolerant to or failed to respond to standard treatment.
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