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Endoscopic endonasal transpterygoid trans lacero-cavernous resection of Knosp 4 functioning pituitary macroadenoma.
J Clin Neurosci
November 2024
Department of Neurosurgery, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
In this video, we demonstrate the technique of endoscopic transpterygoid trans lacerum trans cavernous approach for the excision of Knosp 4 functioning pituitary macroadenomas. We highlight the anatomy and key steps of the approach using cadaveric dissection and present two clinical cases. A 42-year-old female with a growth hormone-secreting tumor and Knosp 4 macroadenoma underwent an extended endoscopic endonasal approach and near-total excision of the tumor.
View Article and Find Full Text PDFLong-term safety of gamma knife radiosurgery (SRS) for acromegaly.
Pituitary
October 2021
Department of Oncology and Metabolism, Medical School, University of Sheffield, Sheffield, UK.
Article Synopsis
- Acromegaly, if left uncontrolled, can lead to serious health issues, and stereotactic radiosurgery (SRS) is an alternative for patients who can't undergo or have failed pituitary surgery, but long-term safety data are limited.
- A study followed 118 patients treated with SRS over 30 years, finding that the incidence of stroke was similar to the normal population, and the average follow-up was 134 months with no significant loss of vision for most patients.
- The findings suggest SRS does not increase stroke risk, and that careful planning with MRI and limiting radiation treatments can reduce complications, particularly for vision-related issues.
Pituitary apoplexy causing spontaneous remission of acromegaly following long-acting octreotide therapy: a rare drug side effect or just a coincidence.
Oxf Med Case Reports
April 2016
Department of Endocrinology , Shri Ram Murti Smarak Institute of Medical Sciences (SRMS IMS), Bareilly, Uttar Pradesh , India.
Pituitary apoplexy is characterized by abrupt onset of haemorrhage or non-haemorrhagic infarction of a pituitary adenoma. The clinical features include acute onset severe headache, visual field defects, meningeal irritation, ophthalmoplegia and hypopituitarism. The pituitary apoplexy may be clinically silent in ∼25% of patients.
View Article and Find Full Text PDFComplete surgical resolution of bilateral total opthalmoplegia without visual field defect in an acromegalic patient presented with pituitary apoplexy.
Endocr J
December 2007
Department of Endocrinology, Erciyes University Medical School, Kayseri, Turkey.
Pituitary apoplexy (PA), which is one of the most serious life-threatening complications of pituitary adenoma, is characterized by abrupt onset of headache, nausea, vomiting, visual disturbances and oculomotor paresis. Combination of oculomotor cranial nerve paralysis with normal visual fields is very rare in PA. We report a 60-year-old acromegalic man presented with panhypopituitarism and bilateral total opthalmoplegia without a visual field defect.
View Article and Find Full Text PDFBlurred vision during airline flight reveals prolactinoma.
Optometry
March 2003
SUNY College of Optometry, New York, New York 10036, USA.
Background: Pituitary adenomas can manifest with a variety of endocrinologic signs and symptoms, including amenorrhea, galactorrhea, infertility, and acromegaly. Because of the anatomic location of the pituitary gland, and its proximity to the optic chiasm and cavernous sinuses, pituitary adenomas can also result in decreased visual acuity, diplopia, ophthalmoplegia, visual-field loss, and optic atrophy. In general, these tumors are slow-growing.
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