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Hypobaric hypoxia drives selection of altitude-associated adaptative alleles in the Himalayan population.
Sci Total Environ
February 2024
Genomics and Molecular Medicine, CSIR-Institute of Genomics and Integrative Biology, Delhi 110007, India; Institute of Hypoxia Research, New Delhi 110067, India. Electronic address:
Genetic variants play a crucial role in shaping the adaptive phenotypes associated with high-altitude populations. Nevertheless, a comprehensive understanding of the specific impacts of different environments associated with increasing altitudes on the natural selection of these genetic variants remains undetermined. Hence, this study aimed to identify genetic markers responsible for high-altitude adaptation with specific reference to different altitudes, majorly focussing on an altitude elevation range of ∼1500 m and a corresponding decrease of ≥5 % in ambient oxygen availability.
View Article and Find Full Text PDF[The comparative characteristics of the clinico-physiological action of electromagnetic radiation in the milli- and nanometer ranges in hypertension].
Vopr Kurortol Fizioter Lech Fiz Kult
February 1999
The sinocarotid zone (SCZ) of 127 patients with essential hypertension (EH) stage I and II was exposed to electromagnetic millimetric and nanometric waves. Differentiated indications for laser and short-wave-frequency therapy on SCZ in EH have been formulated basing on the postexposure changes in blood pressure, main complaints, central and cerebral hemodynamics, lipid metabolism, blood coagulation.
View Article and Find Full Text PDFVisual functions in albinism were examined by psychophysiological and electrophysiological methods. Impaired functioning of light, brightness, and contrast channels of the visual system was revealed, as well as specific electrophysiological parameters typical of this condition: increased wave a and shortened latent periods of waves a and b on the total ERG, reduced amplitude and a shorter latent period of P-100 peak of visual evoked potential, prolonged latent periods of waves a and b of local ERG, and increased amplitude of waves a and b of L-ERG.
View Article and Find Full Text PDF[The clinico-physiological characteristics of biologically active points].
Fiziol Zh (1994)
October 1996
Biological active acupoints (BAAp) are peculiar markers of the reflector and general vegetative reaction. Their particular structure, relation to neuro-humoral regulation in the organism are still disputable. The experimental study confirms the availability of BAAp morphological subject.
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