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JAMA Netw Open
January 2025
Faculty of Medicine, Sana'a University, Sana'a, Yemen.
Importance: Rapid digitalization of health care and a dearth of digital health education for medical students and junior physicians worldwide means there is an imperative for more training in this dynamic and evolving field.
Objective: To develop an evidence-informed, consensus-guided, adaptable digital health competencies framework for the design and development of digital health curricula in medical institutions globally.
Evidence Review: A core group was assembled to oversee the development of the Digital Health Competencies in Medical Education (DECODE) framework.
Brain
January 2025
Reina Sofia Alzheimer Centre, CIEN Foundation, ISCIII, Madrid, Spain.
Lewy body (LB) pathology is present as a co-pathology in approximately 50% of Alzheimer's disease (AD) dementia patients and may even represent the main neuropathologic substrate in a subset of patients with amnestic impairments. However, the degree to which LB pathology affects the neurodegenerative course and clinical phenotype in amnestic patients is not well understood. Recently developed α-synuclein seed amplification assays (αSyn-SAAs) provide a unique opportunity for further investigating the complex interplay between AD and LB pathology in shaping heterogeneous regional neurodegeneration patterns and clinical trajectories among amnestic patients.
View Article and Find Full Text PDFJ Chem Ecol
January 2025
Laboratório de Ecologia Comportamental, Centro de Estudos em Recursos Naturais, Universidade Estadual de Mato Grosso do Sul, Dourados, MS, Brazil.
Cuticular hydrocarbons (CHCs) constitute an important class of chemical compounds present in the cuticular layer of insects, where their main functions are to prevent desiccation of the cuticle and as signals for intraspecific recognition. Studies concerning CHCs have shown a phenotypic flexibility of their composition, depending on environmental factors. However, the way that each of these factors influences this variation remains little explored.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Sorbonne Université, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Paris, France.
Vestibular schwannoma (VS) is a benign tumor that varies in size and presentation. Surgery is the preferred treatment for large or symptomatic VS. Facial nerve (FN) preservation is a priority because of its impact on well-being.
View Article and Find Full Text PDFInt J Hematol
January 2025
Blood Disorders Center, Aiiku Hospital, S4W25, Chuo-ku, Sapporo, 064-0804, Japan.
Chronic graft-versus-host disease (cGVHD) is a major serious complication after allogeneic stem-cell transplantation (allo-HSCT), and often mimics autoimmune diseases. Central nervous system (CNS) symptoms are rare manifestations of cGVHD, and are difficult to diagnose. CNS manifestations of cGVHD were discussed in the 2020 National Institutes of Health cGVHD Consensus Project as one of the "atypical cGVHD manifestations" with involvement of various organ systems other than classical cGVHD organs.
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