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Targeted Activation of OGG1 Inhibits Paraptosis in Lens Epithelial Cells of Early Age-Related Cortical Cataract.
Invest Ophthalmol Vis Sci
January 2025
Eye Institute, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, Jiangsu, China.
Purpose: To investigate potential modes of programmed cell death in the lens epithelial cells (LECs) of patients with early age-related cortical cataract (ARCC) and to explore early-stage intervention strategies.
Methods: Anterior lens capsules were collected from early ARCC patients for comprehensive analysis. Ultrastructural examination of LECs was performed using transmission electron microscopy.
Morphological Features of the Pecten Oculi in the Common Kestrel (Falco tinnunculus).
Anat Histol Embryol
January 2025
Department of Biochemistry, Yozgat Bozok University, Faculty of Veterinary Medicine, Yozgat, Turkey.
This study aimed to investigate the macroscopic, light microscopic (LM) and scanning electron microscopic (SEM) characteristics of the pecten oculi in common kestrels (Falco tinnunculus). A total of six eyeballs from three common kestrels were used as the study material. The examination revealed that the bulbus oculi was spherical in shape and its diameter exceeded the axial-global length.
View Article and Find Full Text PDFSpermatozoa and Spermatogenesis in the Ribbon Worm Asteronemertes gibsoni (Hoplonemertea, Oerstediidae), a Symbiont of Sea Stars.
J Morphol
December 2024
A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, Vladivostok, Russia.
In the phylum Nemertea, the class Hoplonemertea (former Enopla) comprises the largest number of studied species with complex spermatozoa. Asteronemertes gibsoni Chernyshev, 1991, a nemertean species having a symbiotic relationship with sea stars, is characterized by complex filiform spermatozoa. Here, spermatogenesis and spermatozoon structure in A.
View Article and Find Full Text PDFThe interhemispheric amygdala-accumbens circuit encodes negative valence in mice.
Science
November 2024
School of Basic Medical Sciences, State Key Laboratory of Medical Neurobiology, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200032, China.
The structurally symmetric mammalian brain hemispheres are interconnected by commissural axons across the midline. However, the functions of interhemispheric connectivity remain largely unknown. We found that in mice, transection of the anterior commissure (AC), which connects the rostroventral forebrain, impaired avoidant behaviors.
View Article and Find Full Text PDFFrom Trypomastigotes to Trypomastigotes: Analyzing the One-Way Intracellular Journey of by Ultrastructure Expansion Microscopy.
Pathogens
October 2024
Laboratorio de Interacciones Hospedero Patógeno, Institut Pasteur de Montevideo, Montevideo 11400, Uruguay.
The protozoan parasite is the causative agent of Chagas disease, also called American trypanosomiasis. This neglected tropical disease affects millions of individuals across the Americas. To complete its life cycle, parasitizes both vertebrate hosts and its vector, commonly known as the 'kissing bug'.
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