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Synthesis, Characterization, and Docking Studies of Some New Chalcone Derivatives to Alleviate Skin Damage Due to UV Light.
Molecules
February 2025
Department of Pharmaceutical Chemistry, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu 333053, India.
Increasing cases of sunburn is one of the serious problems across the globe. In this connection, there is an urgent requirement for some effective sun screening agents. In the search for the same, nanoemulsions of some new synthesized and characterized chalcone derivatives were prepared and evaluated in vitro and in vivo.
View Article and Find Full Text PDFEvaluating Anti- Potential of . Extract against Healthcare-Associated Infections in Tertiary Hospitals of Al-Kharj Governorate: An Study.
J Pharm Bioallied Sci
December 2024
Department of Basic Medical Sciences, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Background: Healthcare-associated infections (HAIs) caused by pathogens are a significant concern in tertiary hospitals worldwide, including those in Al-Kharj, Saudi Arabia. This study aimed to explore the bioactive compounds from and evaluate their antimicrobial activity against pathogens.
Materials And Methods: Methanolic extracts of the stem were prepared and subjected to phytochemical analysis, thin-layer chromatography (TLC), and antimicrobial testing using the well-diffusion method.
Analytical Methods for Estimating Metformin Hydrochloride, Pioglitazone and Teneligliptin in Diabetes Management: a Comprehensive Review.
J Chromatogr Sci
February 2025
Department of Pharmaceutical Quality Assurance, School of Pharmacy, RK University, Bhavnagar Highway Kasturbadham, Rajkot-360020, Gujarat, India.
Diabetes mellitus remains a global health challenge, with a growing need for effective therapies. Metformin, Pioglitazone and Teneligliptin are widely prescribed medications for diabetes management. Accurate and precise estimation of these drugs is essential to ensure optimal therapeutic efficacy while minimizing side effects.
View Article and Find Full Text PDFPhyto-mediated synthesis can be used for the sustainable fabrication of metallic nanoparticles (NPs). Ethanolic leaf extract of Acacia jacquemontii was used to phyto-fabricate iron oxide nanoparticles (FeO NPs). Synthesized FeO NPs were examined by various analytical techniques for their detailed chemical elemental and morphological features.
View Article and Find Full Text PDFBio-standardization and development of a unique polyherbal formulation with dipeptidyl peptidase -IV inhibitory activity for type 2 diabetes mellitus.
Nat Prod Res
February 2025
Department of Pharmacology, MGM Medical College, Navi Mumbai, India.
Medicinal herbs may provide an alternative source of Dipeptidyl peptidase -IV (DPP-IV) Inhibitors, particularly in light of mounting evidence of high costs and adverse drug reactions associated with synthetic DPP-IV Inhibitors. DPP-IV inhibitory activity of medicinal plants , and was elucidated in previous investigations from our lab. The goal of this work was to develop a polyherbal tablet including these medicinal plants with DPP-IV inhibitory action, conduct bio-standardization investigations, and test its anti-diabetic benefits in the streptozotocin model of Type 2 diabetes.
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