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Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer.
J Transl Med
January 2025
Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, People's Republic of China.
Background: Drug resistance constitutes one of the principal causes of poor prognosis in breast cancer patients. Although cancer cells can maintain viability independently of mitochondrial energy metabolism, they remain reliant on mitochondrial functions for the synthesis of new DNA strands. This dependency underscores a potential link between mitochondrial energy metabolism and drug resistance.
View Article and Find Full Text PDFA Novel Endophytic Fungus R-423 for the Control of Root Rot in Pigeon Pea as Reflected by the Alleviation of Reactive Oxygen Species-Mediated Host Defense Responses.
J Agric Food Chem
January 2025
College of Forestry, Beijing Forestry University, Beijing 100083, People's Republic of China.
root rot is a devastating fungal disease that causes significant yield losses in legume crops. A novel endophytic fungus R-423 isolated from pigeon pea had a significant antagonistic capacity against . R-423 extracts could inhibit growth and cause it to die.
View Article and Find Full Text PDFComposition-Dependent Voltage-Driven OFF-ON Switching of Ferromagnetism in Co-Ni Oxide Microdisks.
ACS Appl Mater Interfaces
January 2025
Departament de Física, Universitat Autònoma de Barcelona, Cerdanyola del Vallès 08193, Spain.
Magneto-ionics, which refers to the modification of the magnetic properties of materials through electric-field-induced ion migration, is emerging as one of the most promising methods to develop nonvolatile energy-efficient memory and spintronic and magnetoelectric devices. Herein, the controlled generation of ferromagnetism from paramagnetic Co-Ni oxide patterned microdisks (prepared upon thermal oxidation of metallic microdisks with dissimilar Co-Ni ratios, i.e.
View Article and Find Full Text PDFChryxanthone A, an extracted substance from endophytic fungal Aspergillus versicolor, produces anti-oxidant neuroprotection possibly via the action on mTOR/CREB axis.
Gene
January 2025
Translational Medicine Center of Pain, Emotion and Cognition, Health Science Center, Ningbo University, Ningbo 315211 Zhejiang, China. Electronic address:
Background: Neurons are susceptible to oxidative stress due to the elevated reactive oxygen species (ROS) production and the limited antioxidant defense mechanisms. Therefore, it is possible to treat oxidative stress-related neurological disorders via the inhibition of oxidative stress. Chryxanthone A is an extracted substance derived from the endophytic fungal Aspergillus versicolor, with an atypical dihydropyran ring.
View Article and Find Full Text PDFPyrolytic conversion of construction, renovation, and demolition (CRD) wood wastes in Québec to biochar: Production, characterization, and identifying relevant stability indices for carbon sequestration.
Sci Total Environ
January 2025
Université du Québec à Trois-Rivières Trois-Rivieres, Quebec, Canada.
Management of heterogeneous construction, renovation, and demolition (CRD) wood residues in Québec brings into light, a widespread topic under discussion related to their current disposal methods in landfills, that may lead to environmental concerns. With rising forfeitures from a legal standpoint, alternative treatment methods for CRD wood wastes are being explored. Thermochemical biomass conversion techniques can be employed to depolymerize low-quality end-of-life CRD wood and valorize it to bio-based products.
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