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Immediate lymphatic reconstruction with targeted lymphatic axillary repair.
J Plast Reconstr Aesthet Surg
December 2024
Department of Plastic Surgery, and Hospital de Sant Pau, Barcelona, Spain. Electronic address:
Current surgical treatment for established lymphedema can be challenging and not always successful. To reduce the incidence of post-operative lymphedema, we began trialing targeted lymphatic axillary repair (TLAR) as a technique for immediate lymphatic reconstruction with the aim of reducing post-operative lymphedema incidence. In this observational prospective study, conducted between March 2017 and May 2022, we assessed the effectiveness of TLAR in reducing lymphedema occurrence in consecutive breast cancer patients who underwent surgery involving axillary lymph node dissection (ALND).
View Article and Find Full Text PDFPrimary Lymphedema: Anatomically Isolated or a Pervasive Systemic Disorder?
Plast Reconstr Surg Glob Open
December 2024
From the Department of Plastic Surgery, Center for Lymphedema Research and Reconstruction, Cleveland Clinic, Cleveland, OH.
Background: Primary lymphedema, a condition characterized by impaired lymphatic function, has long remained underexplored. Current diagnostic approaches rely on clinical history and genetic testing, yet the genetic underpinnings remain elusive in many cases. Traditional thinking suggests that primary lymphedema is confined to specific anatomical regions, but our experience challenges this notion.
View Article and Find Full Text PDFMonitoring lymphatic reconstitution in free latissimus dorsi flap for lower extremity defects repair in pediatric patients: a case series.
Transl Pediatr
November 2024
Department of Burns and Plastic Surgery, Children's Hospital of Nanjing Medical University, Nanjing, China.
Background: The circulation in free flap is mainly studied on blood perfusion, but lack of exploring contributory factor of lymphatic drainage. This study aimed to monitor lymphatic reconstitution of free latissimus dorsi (LD) flaps for lower extremity defects repair, using indocyanine green (ICG) lymphography and assessing its relationship with post-operative flap edema.
Methods: Patients who underwent lower extremity defects repair with free LD flap between January 2021 and April 2024 were included.
Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer.
Radiother Oncol
February 2024
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. Electronic address:
This prospective feasibility trial investigated pulmonary interstitial lymphography to identify thoracic primary nodal drainage (PND). A post-hoc analysis of nodal recurrences was compared with PND for patients with early-stage lung cancer; larger studies are needed to establish correlation. Exploratory PND-inclusive stereotactic ablative radiotherapy plans were assessed for dosimetric feasibility.
View Article and Find Full Text PDFBreast lymphedema following breast-conserving treatment for breast cancer: current status and future directions.
Breast Cancer Res Treat
April 2024
Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.
Article Synopsis
- The study aims to evaluate current knowledge on breast lymphedema (BL) diagnosis and treatment post-breast-conserving surgery, identify gaps, and suggest future research directions.
- A literature review covering studies from 2000 to 2023 found variations in BL incidence and risk factors, with promising diagnostic methods like tissue dielectric constant and ultrasound, but lacking standardized criteria and strong treatment evidence.
- The authors conclude that more comprehensive studies are needed to clarify BL’s natural history and improve screening, diagnostic approaches, and treatment guidelines for patients.
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