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Antiretroviral Use for HIV Prevention During Pregnancy: The Need to Strengthen Regulatory and Surveillance Systems in Africa.
Drug Saf
January 2025
Forum for Collaborative Research, University of California, Berkeley, Washington, DC, USA.
HIV-prevention efforts focusing on women of child-bearing potential are needed to end the HIV epidemic in the African region. The use of antiretroviral drugs as pre-exposure prophylaxis (PrEP) is a critical HIV prevention tool. However, safety data on new antiretrovirals during pregnancy are often limited because pregnant people are excluded from drug development studies.
View Article and Find Full Text PDFThe role of D-dimer changes in predicting delivery time in preterm premature rupture of membranes: a retrospective analysis.
Arch Gynecol Obstet
January 2025
Department of Obstetrics and Gynecology, Division of Perinatology, Ankara Etlik City Hospital, Ankara, Turkey.
Introduction: Pregnancy induces a hypercoagulable state, characterized by increased coagulation factors and decreased anticoagulants, alongside ongoing fibrinolysis marked by elevated D-dimer (DD) levels. Reference values for DD in pregnancy often exceed the non-pregnant cutoff due to these changes. Elevated DD levels are common in late pregnancy and may correlate with complications such as gestational diabetes, hypertension, and preterm delivery, particularly in cases of preterm premature rupture of membranes (PPROM).
View Article and Find Full Text PDFIdiopathic subglottic stenosis in a 32-year-old pregnant woman.
Eur Clin Respir J
January 2025
Department of Clinical Medicine, Aarhus University & Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark.
Diagnosis of subglottic stenosis remains greatly a challenge for physicians due to case rarity and presentation of symptoms imitating several other more prevalent medical disorders. Idiopathic subglottic stenosis most often occurs in previously healthy perimenopausal Caucasian women. Several cases have reported symptom progression and increased stenosis, during or in between pregnancies in younger women.
View Article and Find Full Text PDFExtreme Prematurity: A Case Report on the Importance of Multidisciplinary Consultations Before and After Maternity Ward Discharge.
Cureus
December 2024
Pediatrics, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Extreme prematurity involves a series of complications that a multidisciplinary team should manage. Taking into account the risks related to premature newborns, such as maternal-fetal infections, intrauterine growth restriction, and certain comorbidities associated with young gestational age, our objective is to highlight the importance of a multidisciplinary team in approaching cases with an unfavorable prognosis. This is a case report of an extremely preterm newborn who came from a high-risk pregnancy and needed long-term hospitalization in the Neonatal Intensive Care Unit (NICU) and mechanical ventilation.
View Article and Find Full Text PDFWorkplace Ergonomic Adjustments and Supportive Policies During the Pregnancy of a Paint Sprayer: A Case Report.
Cureus
December 2024
Faculty of Medical Sciences, The University of the West Indies, St. Augustine, TTO.
A 29-year-old paint sprayer presented with mild lower back pain and fatigue related to prolonged standing and repetitive tasks in the first few weeks of pregnancy. An initial assessment included a review of her workstation, evaluation of posture, and standard prenatal tests such as routine blood work and ultrasound. These investigations showed normal fetal development and no complications.
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