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An Injectable Alginate Hydrogel Modified by Collagen and Fibronectin for Better Cellular Environment.
ACS Appl Bio Mater
January 2025
Division of Plastic Surgery, Department of Surgery, Yale School of Medicine, Yale University, 310 Cedar Street, New Haven, Connecticut 06510, United States.
Encapsulating fibroblasts in alginate hydrogels is a promising strategy to promote wound healing. However, improving the cell function within the alginate matrix remains a challenge. In this study, we engineer an injectable hydrogel through mixing alginate function with collagen and fibronectin, creating a better microenvironment for enhancing fibroblast function and cytokine secretion.
View Article and Find Full Text PDFSuccessful Diagnosis of a SMARCA4-Deficient Undifferentiated Tumor via Endobronchial Ultrasound-Guided Fine Needle Aspiration and Endobronchial Biopsies.
Cureus
December 2024
Pulmonary and Critical Care, Brody School of Medicine, East Carolina University, Greenville, USA.
Lung cancer is the third most prevalent cancer, following breast cancer in women and prostate cancer in men. However, it remains the leading cause of cancer-related mortality. As treatment options have advanced, the significance of accurate diagnosis has increased, enabling targeted and more personalized therapeutic treatments.
View Article and Find Full Text PDFOutcomes of a pilot randomized clinical trial testing brief interventions to increase HIV pre-exposure prophylaxis uptake among rural people who inject drugs attending syringe services programs.
Ther Adv Infect Dis
January 2025
Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA.
Background: Kentucky is one of seven states with high, sustained rural HIV transmission tied to injection drug use. Expanding access to pre-exposure prophylaxis (PrEP) has been endorsed as a key HIV prevention strategy; however, uptake among people who inject drugs (PWID) has been negligible in rural areas. Syringe services programs (SSPs) have been implemented throughout Kentucky's Appalachian region, providing an important opportunity to integrate PrEP services.
View Article and Find Full Text PDFValidation of existential fulfillment scale in Chinese university students.
Front Psychol
January 2025
School of Psychology, Fujian Normal University, Fuzhou, Fujian, China.
Introduction: This study aimed to assess the psychometric properties of the Existential Fulfillment Scale (EFS) in a Chinese university student sample, emphasizing the cultural fit of the scale.
Methods: A cohort of 1,600 undergraduate students from six universities in Fujian Province completed questionnaires including the EFS, Meaning of Life Questionnaire (MLQ), Index of Well-Being (IWB), and Self-Depression Scale (SDS). We conducted item analysis, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and assessments of criterion-related validity, internal consistency, and test-retest reliability.
Psychological Distress in Adults With Myocardial Infarction: Implications for Health Care Utilization and Expenditure.
JACC Adv
February 2025
Department of Cardiology, Barbra Streisand Women's Heart Center, Cedars Sinai- Smidt Heart Institute, Los Angeles, California, USA.
Background: Myocardial infarction (MI) poses a major financial burden on the U.S. health care system, but its impact on medical expenses and health care utilization when coupled with psychological distress remains unknown.
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