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Background: Vaginal atresia (VA) is a rare female genital tract malformation characterized by the absence or incomplete development of the vagina, often leading to cyclic abdominal pain and menstrual blood retention in adolescent patients. Vaginal atresia is often accompanied by multiple organ malformations. The condition poses significant challenges in diagnosis and management, requiring a multidisciplinary approach.
View Article and Find Full Text PDFDifferential bone calcium retention with the use of oral versus vaginal hormonal contraception: A randomized trial using calcium-41 radiotracer.
Contraception
November 2024
Department of Nutrition Science, Purdue University, West Lafayette, IN, USA.
Objectives: This study aimed to assess if hormonal contraception administered orally (combined oral contraceptive pill, COC) or vaginally (contraceptive vaginal ring) differentially affected bone calcium retention in young females.
Study Design: Reproductive aged females (18-35 years) not using hormonal contraception were dosed with 50 nCi Ca as CaCl in 10 mL of sterile saline (0.9%).
Introduction: Women with polycystic ovary syndrome (PCOS) experience various metabolic, endocrine, reproductive and psychosocial manifestations. Lifestyle modification is crucial for the management of PCOS to reduce long-term complications. Nonetheless, the efficacy and acceptability of lifestyle interventions differs, and there are no uniform methods of clinical application.
View Article and Find Full Text PDFA Study of Non-alcoholic Fatty Liver Disease in Patients With Hypothyroidism: A Cross-Sectional Study in a Tertiary Care Hospital.
Cureus
September 2024
General Medicine, Dr. D.Y. Patil Medical College, Hospital, and Research Centre, Pune, IND.
Background Hypothyroidism occurs when the thyroid gland is underactive and fails to produce sufficient thyroid hormones. It can affect multiple organs including the heart, brain, liver, kidneys, and reproductive system, leading to symptoms such as fatigue, cognitive impairment, elevated cholesterol, fluid retention, fatty liver, and menstrual irregularities. Given the higher prevalence of fatty liver disease in patients with hypothyroidism, it is important to evaluate the need for routine screening for fatty liver in these patients.
View Article and Find Full Text PDFA Case Report of Hematometrocolpos in Two Adolescents: Divergent Clinical Presentations and Diagnostic Challenges.
Cureus
August 2024
Medical Education, Brunel Medical School, London, GBR.
Article Synopsis
- Hematometrocolpos is a rare congenital condition in girls caused by an imperforate hymen, leading to the buildup of menstrual blood and often resulting in abdominal pain.
- The case study presents two adolescent girls who experienced symptoms such as lower abdominal pain, constipation, and urinary retention, and were diagnosed with this condition through a physical exam and ultrasound.
- Successful hymenotomy was performed on both patients, allowing for complete recovery without complications, highlighting the importance of early diagnosis to prevent potential future issues like infertility.
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