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Stress negatively impacts university students, leading to adverse outcomes. While canine-assisted intervention (CAI) has been shown to reduce self-reported stress, no studies have investigated stress levels and associated biomarkers in dogs and students simultaneously. This study examined salivary cortisol, blood pressure, and pulse rate in 122 university students experiencing self-reported moderate to high stress before an encounter with a dog (T1), immediately before meeting a dog (T2), and after spending 15 minutes interacting with a dog (T3).

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The power of interspecific sociality: how humans provide social buffering for horses.

Anim Cogn

March 2025

Department of Environmental, Biological and Pharmaceutical Sciences & Technologies, University of Campania Luigi Vanvitelli, 81100, Caserta, Italy.

In this study, we assessed the interspecific "social buffering effect" of humans on horses, exploring how human presence influences stress responses in horses in an unfamiliar environment using the "isolation paradigm." We examined nine Haflinger horses under two counterbalanced conditions: with a passive human stranger (social condition) or alone (isolation condition). Stress responses were assessed through cortisol measurements, heart rate monitoring, and behavioral observations.

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Study on the regularity of blood pressure changes in pregnant women and its influencing factors.

BMC Pregnancy Childbirth

March 2025

Department of Anesthesia Surgery, The First Hospital of Hebei Medical University, No. 89 Donggang Road, Yuhua District, Shijiazhuang, 050030, China.

Objective: To explore the patterns and influencing factors of blood pressure changes in pregnant women at different stages of pregnancy.

Method: A retrospective analysis of 445 pregnant women who underwent prenatal examination and delivered at the First Hospital of Hebei Medical University between December 2016 and November 2017. A questionnaire survey was conducted on pre-pregnancy information, and data was collected from pre-pregnancy blood routines, blood lipids, cortisol levels, and other biochemical indicators, as well as blood pressure measurements taken before pregnancy, in early pregnancy, mid-pregnancy, and late pregnancy.

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Insomnia is common in type 2 diabetes mellitus (T2DM) and affects mental health and quality of life. The present study aimed to examine the efficacy of MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on the anthropometric measurements, sleep quality, depression, anxiety, and serum levels of cortisol and brain derived neurotrophic factor (BDNF) in type 2 diabetic women with insomnia. This randomized controlled trial (RCT) involved 44 type 2 diabetic women with insomnia, aged 30 to 65 years, who were randomly assigned to be under the MIND low-calorie diet (n = 22) or a low-calorie diet (LCD) as the control group (n = 22) for 12 weeks.

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Background: Methylprednisolone is still used to treat adults with septic shock in real-world clinical settings, despite current international guidelines recommending hydrocortisone. The aim of this study was to assess the effect of methylprednisolone vs hydrocortisone on 30-day mortality among critically ill patients with septic shock.

Methods: We conducted a retrospective cohort study on adults with septic shock using the MIMIC-IV v3.

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