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Systematic bias in malaria parasite relatedness estimation.
G3 (Bethesda)
January 2025
Infectious Disease Epidemiology and Analytics G5 Unit, Institut Pasteur, Université Paris Cité, Paris 75015, France.
Genetic studies of Plasmodium parasites increasingly feature relatedness estimates. However, various aspects of malaria parasite relatedness estimation are not fully understood. For example, relatedness estimates based on whole-genome-sequence (WGS) data often exceed those based on sparser data types.
View Article and Find Full Text PDFNovel genetic insight for psoriasis: integrative genome-wide analyses in 863 080 individuals and proteome-wide Mendelian randomization.
Brief Bioinform
November 2024
Department of Dermatology, Daping Hospital, Army Medical University, No. 10, Changjiang Branch Road, Yuzhong District, Chongqing 400042, China.
Psoriasis affects a significant proportion of the worldwide population and causes an extremely heavy psychological and physical burden. The existing therapeutic schemes have many deficiencies such as limited efficacies and various side effects. Therefore, novel ways of treating psoriasis are urgently needed.
View Article and Find Full Text PDFInvestigating Smartphone-Based Sensing Features for Depression Severity Prediction: Observation Study.
J Med Internet Res
January 2025
Department of Clinical Psychology and Psychotherapy, Institute of Psychology and Education, Ulm University, Ulm, Germany.
Background: Unobtrusively collected objective sensor data from everyday devices like smartphones provide a novel paradigm to infer mental health symptoms. This process, called smart sensing, allows a fine-grained assessment of various features (eg, time spent at home based on the GPS sensor). Based on its prevalence and impact, depression is a promising target for smart sensing.
View Article and Find Full Text PDF"Nobody Seemed to Notice My Work": The Lived Experiences of Home Care Workers Assisting People With Chronic Diseases: A Phenomenological Study.
J Prim Care Community Health
January 2025
University of Rome Tor Vergata, Roma, Lazio, Italy.
Introduction: Home care workers (HCWs) are paid caregivers who provide support to patients with chronic conditions and functional limitations. Additionally, they provide emotional support to patients and familial support. Although several qualitative studies have been conducted on HCWs, they focused more on studying prevalently the lived experiences about the workplace violence, the end of life, stressor and resilience, during the COVID-19 pandemic or focused more in dementia and heart failure, but not on feelings and working conditions.
View Article and Find Full Text PDFA positive empathy intervention to improve well-being on Instagram.
Emotion
January 2025
Department of Psychology, University of Toronto, Scarborough.
With more than half the global population on social media, there is a critical need to understand how to engage it in a way that improves rather than worsens user well-being. Here, we show that positive empathy is a promising tool. Participants who received brief positive empathy instructions before 10 min of browsing their own Instagram feed showed greater affective well-being (Studies 1-4) and life satisfaction (Study 4) at posttest relative to participants who were instructed to browse as usual.
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