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Introduction And Objectives: Pulmonary vein (PV) isolation is one of the cornerstones of rhythm-control therapy for symptomatic atrial fibrillation (AF) patients. Pulsed field ablation (PFA) is a novel ablation modality that involves the application of electrical pulses causing cellular death, and it has preferential tissue specificity. In this study, we aimed to share a one-year single center experience of AF ablation with PFA.

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Neuromodulation comes into focus as a non-pharmacological therapy with the vagus nerve as modulation target. The auricular vagus nerve stimulation (aVNS) has emerged to treat chronic diseases while re-establishing the sympathovagal balance and activating parasympathetic anti-inflammatory pathways. aVNS leads still to over and under-stimulation and is limited in therapeutic efficiency.

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Background: Prader-Willi Syndrome (PWS) is a genetic neurodevelopmental disorder marked by disruptions in circadian rhythms and autonomic nervous system (ANS) activity, hyperphagia, and episodes of emotional outbursts. Previous trials suggest that both invasive and non-invasive vagus nerve stimulation (VNS) can reduce emotional outbursts in PWS, potentially through its effects on vagal activity.

Aim: This case series investigated the effects of transcutaneous auricular VNS (taVNS) on cardiac markers of circadian vagal activity, specifically heart rate variability (HRV) and heart rate (HR), and their potential links to improvements in emotional outbursts.

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Objective: To assess the association between electrocardiogram (ECG) patterns according to the MVP ECG risk score (morphology-voltage-P-wave duration) and a diagnosis of Atrial Fibrillation (AF).

Design: Prospective observational cohort study (1/01/2023-31/12/2024). SITE: Primary care.

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Safety and efficacy of electric cardioversion in the emergency department: analysis of associated factors according to gender.

Emergencias

June 2024

Área de Urgencias, Hospital Clínic de Barcelona, España. Grup de Recerca Urgències, Processos i Patologies, Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS). Unitat de Fibril·lació Auricular, Hospital Clínic de Barcelona, España. Grupo de Arritmias y Síncope. Sociedad Española de Urgencias y Emergencias.

Objective: To explore the safety and effectiveness of electric cardioversion to treat atrial fibrillation in a hospital emergency department (ED).

Methods: Retrospective observational study in a hospital ED. We reviewed episodes of atrial fibrillation in patients aged 18 years orolder treated with cardioversion in our ED or referred for scheduling of cardioversion.

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