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Current research and guidelines for euthanasia in laboratory fish with a focus on fathead minnows.
Lab Anim
January 2025
Environment and Climate Change Canada, Burlington, Canada.
This paper reviews the methods and approaches used to humanely anesthetize (render unconscious) and or euthanize (kill) laboratory fish (in research settings), with a specific focus on the fathead minnow. We surveyed the literature (333 scientific studies published 2004-2021) to examine euthanasia methods used for various life stages. Our findings showed that many published scientific papers do not provide an adequate description of anesthesia or euthanasia methods, particularly for larval fathead minnows.
View Article and Find Full Text PDFComparison of tegoprazan and proton pump inhibitors for first-line eradication: a systematic review with meta-analysis.
Expert Rev Anti Infect Ther
January 2025
Department of Medical Biostatistics, Soonchunhyang University Hospital, Seoul, Korea.
Background: Tegoprazan (TPZ), a potassium-competitive acid blocker with potent gastric acid-suppressing activity, may be a potential agent for treating Helicobacter pylori infection. The study aimed to evaluate the efficacy of TPZ-based therapy for H. pylori eradication compared with proton pump inhibitor (PPI)-based therapy.
View Article and Find Full Text PDFA Noncatalytic Cysteine Residue Modulates Cobalamin Reactivity in the Human B Processing Enzyme CblC.
Biochemistry
January 2025
Laboratory of Clinical Biochemistry and Metabolism, Department of General Pediatrics, Adolescent Medicine and Neonatology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg im Breisgau 79106, Germany.
Human CblC catalyzes the indispensable processing of dietary vitamin B by the removal of its β-axial ligand and an either one- or two-electron reduction of its cobalt center to yield cob(II)alamin and cob(I)alamin, respectively. Human CblC possesses five cysteine residues of an unknown function. We hypothesized that Cys149, conserved in mammals, tunes the CblC reactivity.
View Article and Find Full Text PDFHigh-Performance Mechano-Sensitive Piezoelectric Nanogenerator from Post-Treated Nylon-11,11 Textiles for Energy Harvesting and Human Motion Monitoring.
ACS Appl Mater Interfaces
January 2025
School of Materials Science and Engineering, Henan Key Laboratory of Advanced Nylon Materials and Application, Zhengzhou University, Zhengzhou 450001, China.
Piezoelectric polymer textiles offer distinct advantages in the fabrication of wearable nanogenerators (NGs). One effective strategy to enhance the output capacity of NGs is to modulate the piezoelectric performance of the textiles. This paper focuses on further improving the piezoelectric properties of nylon-11,11 textiles through post-drawing and annealing treatments.
View Article and Find Full Text PDFDetecting noncredible symptomology in ADHD evaluations using machine learning.
J Clin Exp Neuropsychol
January 2025
Department of Psychology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Introduction: Diagnostic evaluations for attention-deficit/hyperactivity disorder (ADHD) are becoming increasingly complicated by the number of adults who fabricate or exaggerate symptoms. Novel methods are needed to improve the assessment process required to detect these noncredible symptoms. The present study investigated whether unsupervised machine learning (ML) could serve as one such method, and detect noncredible symptom reporting in adults undergoing ADHD evaluations.
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