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Evaluation and management of functional biliary pain in patients with an intact gallbladder.
Expert Rev Gastroenterol Hepatol
June 2009
Professor of Medicine, Division of Gastroenterology and Hepatology, Scottsdale, AZ 85259, USA.
The diagnosis and management of suspected functional biliary pain in patients with an intact gallbladder remains contentious. Major issues include the lack of a clear definition of what constitutes biliary pain, a poor understanding of its natural history and pathophysiology, and the all too common scenario of the patient who has persistent pain despite surgical removal of the gallbladder. As a consequence, symptoms alone have generally been considered to be unreliable in the diagnosis of gallbladder dysfunction, and this has led to a search for a reliable test to help confirm a clinical suspicion of gallbladder dysfunction prior to the definitive treatment, cholecystectomy.
View Article and Find Full Text PDFSphincter of Oddi dysfunction in hypercholesterolemic rabbits.
Eur J Gastroenterol Hepatol
March 2008
Department of Radiology, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China.
Background And Objectives: The mechanisms that trigger gallbladder evacuation dysfunction, the key risk factor for gallstone formation, have not yet been fully elucidated. The sphincter of Oddi (SO) plays important roles in the regulation of gallbladder evacuation and maintenance of normal hydraulic pressure of the biliary tract. The aim of our study was to investigate the effects of hypercholesterolemia on the motility function of SO and the underlying mechanisms of SO dysfunction (SOD).
View Article and Find Full Text PDFOutcomes of surgical therapy for biliary dyskinesia.
J La State Med Soc
October 2003
Department of Surgery, Louisiana State University Health Sciences Center, Shreveport, USA.
Patients with biliary dyskinesia have biliary colic, a normal gallbladder ultrasound, and a gallbladder ejection fraction typically less than 35%. We report a retrospective review of 70 patients with biliary dyskinesia who underwent cholecystectomy. Seventy-seven percent of the patients were women.
View Article and Find Full Text PDFValue of measuring gallbladder motility in clinical practice.
Dig Liver Dis
July 2003
Internal Medicine 1, Spedali Civili and University of Brescia, 25100 Brescia, Italy.
Measurement of gallbladder motility is a powerful research tool, but its value in clinical practice is uncertain. Three main conditions have been investigated for potential clinical application of this measurement. The first potential application is for identification of patients at risk of recurrence following gallstone dissolution with medical therapy.
View Article and Find Full Text PDFThe study between the dynamics and the X-ray anatomy and regularizing effect of gallbladder on bile duct sphincter of the dog.
World J Gastroenterol
May 2003
Radiology Department of Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, Shaanxi Province, China.
Aim: To study the relationship between the radiological anatomy and the dynamics on bile duct sphincter in bile draining and regularizing effect of gallbladder.
Methods: Sixteen healthy dogs weighing 18 kg to 25 kg were divided randomly into control group and experimental group (cholecystectomy group). Cineradiography, manometry with perfusion, to effect of endogenous cholecystokinin and change of ultrastructure were employed.
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