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Purpose: Recent research suggests that caffeine use may promote a range of adjustment difficulties among adolescents, particularly during the middle school years. The effects of caffeine are particularly concerning given the increased use of high-dosage caffeine products, such as energy drinks, among youth. We investigated the influence of caffeine use on trajectories of conduct problems among early adolescents.

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The aim of this study was to investigate the effects of caffeine, vanillin, and epigallocatechin gallate on salivation and swallowing and to find ways to correct their negative effects. Solutions of these substances with an equivalent intensity of bitter taste were compared for this purpose. To compensate for their effect, solutions of adenosine monophosphate, saliva substitute, and their combination were used.

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Introduction: Functional beverages are increasingly popular but it is important to validate their purported effects through research. The aim of the current study was to investigate the effects of a new functional energy shot on cognitive performance and mood states in healthy adults, with a focus on measuring mental energy enhancement and attenuation of negative effects associated with extended performance of mentally demanding tasks.

Methods: This study was a randomized, double-blind, placebo-controlled, crossover trial.

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The safety of traditional Chinese medicine (TCM) herbal remedies, particularly when used with modern medications or in non-traditional dosages, requires careful consideration. We present a case of a 62-year-old male with pre-existing cardiovascular risk factors who developed tachycardia-induced cardiomyopathy (TIC) potentially linked to prolonged use of the TCM supplement "Tan Ke Jing." The supplement contains licorice root, caffeine, and apricot kernel, which have known cardiovascular effects.

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Immune and metabolic factors play an important role in the onset and development of insomnia. This study aimed to investigate the causal relationship between insomnia and immune cells and metabolites. Data for 731 immune cell phenotypes, 1400 metabolites, and insomnia in this study were obtained from the GWAS open-access database.

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