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Consumer-oriented (patient and family) outcomes from nursing in genomics: a scoping review of the literature (2012-2022).
Front Genet
November 2024
Global Genomics Nursing Alliance (G2NA) and William F. Connell School of Nursing, Boston College, Chestnut Hill, MA, United States.
Introduction: Genomics is a lifespan competency that is important for improving health outcomes for individuals, families, and communities. Nurses play a key role in genomic healthcare and realizing the potential of the genomic era.
Methods: We aimed to chart the current state of genomics in nursing by conducting a systematic scoping review of the literature in four databases (2012-2022).
Transcriptomic Remodeling Occurs During Cambium Activation and Xylem Cell Development in .
Curr Issues Mol Biol
October 2024
College of Horticulture and Forestry Science, Huazhong Agricultural University, Wuhan 430070, China.
Article Synopsis
- The research focuses on the cambium activity in a tree species extensively cultivated in the Yangtze River’s wetlands, highlighting its ecological and timber importance.
- Using RNA sequencing, the study identifies key genes involved in cambium cell differentiation across three growth stages: dormancy, reactivation, and activity.
- Findings suggest that specific genes play crucial roles in regulating transcription during lignin formation, revealing the dynamic transcriptional changes associated with vascular cambium development and wood formation.
Study protocol for a randomized controlled trial of Adapt 2 Asthma (A2A), a culturally relevant coping skills and asthma management intervention for Latinx Families.
Trials
October 2024
Department of Educational Psychology, University of Texas at Austin, 1912 Speedway, Stop D5000, Austin, TX, 78712, USA.
Background: Latinx children in the United States experience disparities in asthma control and asthma-related functional outcomes compared to non-Latinx White children, including more school absences, emergency department visits, and hospitalizations for asthma. Stress appears to play a role in asthma control, but interventions designed to address the role of stress in asthma control for Latinx children are limited.
Method: The current randomized controlled trial tests the effects of Adapt 2 Asthma (A2A), a family-based coping skills and asthma management intervention tailored to the stressors, strengths, and cultural beliefs of Latinx families, compared to an asthma self-management control arm (the Asthma Plan for Kids; APK).
Improving multiple stressor-response models through the inclusion of nonlinearity and interactions among stressor gradients.
Environ Monit Assess
October 2024
School of Natural Sciences, Trinity College Dublin, The University of Dublin, Dublin, Ireland.
Article Synopsis
- Stressor-response models help track changes in ecosystems caused by human activities and natural factors, but often overlook nonlinearity and stressor interactions.
- An analysis of data from 177 Irish river sites revealed that incorporating nonlinearity improves five out of six biological response models, and all models benefitted from considering interactions between stressors.
- The study highlights that the relationship between stressors and their ecological impact can depend on other environmental factors, suggesting that more complex modeling techniques are necessary for effective ecosystem management.
Mirtazapine to alleviate severe breathlessness in patients with COPD or interstitial lung diseases (BETTER-B): an international, multicentre, double-blind, randomised, placebo-controlled, phase 3 mixed-method trial.
Lancet Respir Med
October 2024
Clinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, UK.
Background: Breathlessness frequently becomes severe among people with respiratory disease. Mirtazapine, a widely used antidepressant, has shown promise in the modulation of respiratory sensation and the response to it, as well as reducing feelings of panic, which often accompanies breathlessness. We aimed to determine the effectiveness of mirtazapine to alleviate severe persisting breathlessness.
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