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Dynamics of anti-malarial antibodies in non-immune patients during and after a first and unique Plasmodium falciparum malaria episode.
Malar J
June 2020
Department of Infectious-Tropical Diseases and Microbiology, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Verona, Italy.
Background: Malaria is a major travel medicine issue. Retrospective confirmation of a malaria episode diagnosed in an endemic area can have relevant implications in transfusional medicine in Europe, where blood donors are excluded from donation on the basis of positive malaria serology. However, there is scarce evidence on the dynamics of anti-malarial antibodies after a first malaria episode in non-immune individuals.
View Article and Find Full Text PDF[Malaria: immuno-permissive management in the prevention of transfusional malaria].
Transfus Clin Biol
September 2019
CNR du Paludisme, hôpital Bichat, AP-HP, 46, rue Henri Huchard, 75018 Paris, France. Electronic address:
Malaria is a potentially life-threatening tropical infectious disease caused by a parasite that infects erythrocytes. Its transmission is vectorial, but the transfusion of infected red blood cells can cause a delicate diagnosis of transmitted malaria. Prevention is based on the selection of donors at risk by the search for antibodies reflecting past infection, in the absence of a sufficiently sensitive parasite detection technique to prevent all risks.
View Article and Find Full Text PDFSummary: . Transfusional malaria is an accidental transmission of via a blood transfusion. Its magnitude is underestimated and very little data on the assessment of this risk are available in Niger.
View Article and Find Full Text PDFTherapeutic Macromolecular Iron Chelators.
Curr Med Chem
April 2019
Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad 500037, India.
Iron is a key element for every single living process. On a fundamental level, targeting iron is a valuable approach for the treatment of disorders caused by iron overload. Utilizing iron chelators as therapeutic agents has received expanding consideration in chelation therapy.
View Article and Find Full Text PDFTransfusional malaria in the neonatal period in Lagos, South-West Nigeria.
PLoS One
July 2018
Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria.
Background And Objectives: Sick neonates in malaria endemic areas are frequently transfused with donor blood unscreened for malaria parasite. Consequently, they are at risk of transfusional malaria which can lead to increased neonatal mortality. The study aimed to determine the burden of transfusional malaria in neonates to help in policy formulation on prevention of transfusional malaria.
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