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Historic Treponema pallidum genomes from Colonial Mexico retrieved from archaeological remains.
PLoS Negl Trop Dis
June 2018
Institute for Archaeological Sciences, University of Tübingen, Tübingen, Germany.
Treponema pallidum infections occur worldwide causing, among other diseases, syphilis and yaws. In particular sexually transmitted syphilis is regarded as a re-emerging infectious disease with millions of new infections annually. Here we present three historic T.
View Article and Find Full Text PDFBone lesions in yaws - another potential marker of indigenous Australian remains.
Forensic Sci Med Pathol
December 2017
Adelaide Medical School, The University of Adelaide, Level 3 Medical School North Building, Frome Road, Adelaide,, 5005, Australia.
Yaws Osteoperiostitis Treated with Single-Dose Azithromycin.
Am J Trop Med Hyg
May 2017
Barcelona Institute for Global Health, Hospital Clínic, University of Barcelona, Barcelona, Spain.
AbstractThe etiologic agent of yaws, subsp. , causes a multistage infection transmitted by nonsexual contact with the exudates from active lesions. Bone lesions in the form of osteoperiostitis are common and occur in numerous bones simultaneously in early stages.
View Article and Find Full Text PDFTools for opening new chapters in the book of Treponema pallidum evolutionary history.
Clin Microbiol Infect
November 2016
Epidemiology of Highly Pathogenic Microorganisms, Germany. Electronic address:
Treponema pallidum infections causing yaws disease and venereal syphilis are globally widespread in human populations, infecting hundreds of thousands and millions annually respectively; endemic syphilis is much less common, and pinta has not been observed in decades. We discuss controversy surrounding the origin, evolution and history of these pathogens in light of available molecular and anthropological evidence. These bacteria (or close relatives) seem to affect many wild African nonhuman primate (NHP) species, though to date only a single NHP Treponema pallidum genome has been published, hindering detection of spillover events and our understanding of potential wildlife reservoirs.
View Article and Find Full Text PDFOsteoperiostitis in early yaws: case series and literature review.
Clin Infect Dis
March 2011
Department of Medicine, Lihir Medical Centre, International SOS, Lihir Island, Papua New Guinea.
We describe the clinical and radiological manifestations and outcome after treatment of 7 children who received a diagnosis of early yaws osteoperiostitis. Osteoperiostitis occurred some weeks after the primary infection, and the most common finding was hypertrophic periostitis of long bones. All treated patients had excellent responses to benzyl-penicillin therapy.
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