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Madecassoside mitigates acute myocardial infarction injury by activating the PKCB/SPARC signaling pathway.
Acta Pharmacol Sin
January 2025
Key Laboratory of Cardiovascular and Cerebrovascular Medicine, School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China.
The current treatments and drugs of myocardial infarction (MI) remain insufficient. In recent years, natural products have garnered significant attention for their potential in treating cardiovascular diseases due to their availability and lower toxicity. Saponins, in particular, showed promising effects for cardiac protection.
View Article and Find Full Text PDFCardiac dose comparison of abdominal and thoracic deep inspiration breath hold in adult female with left-sided breast cancer receiving radiation therapy: A systematic review and meta-analysis.
Radiography (Lond)
January 2025
School of Nursing, The Hong Kong Polytechnic University, Hong Kong. Electronic address:
Introduction: Deep inspiration breath hold technique has shown promise in reducing cardiac toxicity and improving patient outcomes. However, there is a lack of consensus regarding the implementation of abdominal breath hold technique and its impact on cardiac dose. This systematic review and meta-analysis aim to provide insights into the comparative effectiveness of abdominal and thoracic breath hold in mitigating cardiac toxicity during radiation therapy for left-sided breast cancer.
View Article and Find Full Text PDFMicrosurgical clipping of blood blister-like anterior communicating artery aneurysm in a patient with total occlusion of left internal carotid artery aneurysm.
World Neurosurg
January 2025
Department of Neurosurgery, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Case Series of Right-Hemisphere Nonfluent Variant of Primary Progressive Aphasia.
J Clin Neurol
January 2025
Brain and Mind Centre, The University of Sydney, Camperdown, NSW, Australia.
Background And Purpose: Nonfluent variant primary progressive aphasia (nfvPPA) is a neurodegenerative disorder characterized by the progressive deterioration of language functions that typically appears with atrophy predominating in the left peri-insular region (left-nfvPPA) on imaging. While both left-dominant and right-dominant presentations have been reported in semantic variant primary progressive aphasia, the other language presentation of frontotemporal dementia, no case series of nfvPPA with predominantly right-sided atrophy of the peri-insular region (right-nfvPPA) have been reported previously. This study explored whether such entities exist and what their clinical features might be.
View Article and Find Full Text PDFExperientially-grounded and distributional semantic vectors uncover dissociable representations of conceptual categories.
Lang Cogn Neurosci
July 2023
Cognition and Brain Sciences Unit, Medical Research Council, Cambridge, UK.
Neuronal populations code similar concepts by similar activity patterns across the human brain's semantic networks. However, it is unclear to what extent such meaning-to-symbol mapping reflects distributional statistics, or experiential information grounded in sensorimotor and emotional knowledge. We asked whether integrating distributional and experiential data better distinguished conceptual categories than each method taken separately.
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