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Similar Publications

Background: Coal miners are highly prone to occupational health risks, such as black lung disease. This study aims to assess the prevalence of black lung disease and the factors associated with black lung disease among coal miners in Asia.

Method: This systematic review, conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, searched through the scientific literature of the following databases: EBSCO, ScienceDirect, PubMed, and Scopus.

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Article Synopsis
  • Spirometry is the main test for assessing lung function in coal miners, but it may not fully capture lung impairment; researchers aimed to examine a different measure, called single-breath diffusing capacity for carbon monoxide (D), in former coal miners.
  • Analysis of data from over 3,100 former miners revealed that 20.2% showed diffusion impairment, with a notable portion (10%) of those with normal spirometry also affected.
  • The study concluded that diffusion impairment is common among former miners, suggesting that incorporating D tests into evaluations can better detect early lung disease alongside traditional spirometry.
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Alpha-1 antitrypsin (AAT) deficiency, an autosomal co-dominant inherited condition, significantly impacts lung and liver functions, with mutations in the SERPINA1 gene, notably the Z allele, playing a pivotal role in disease susceptibility. This retrospective descriptive study from a rural Eastern Kentucky pulmonary clinic aimed to characterize patients with AAT deficiency, focusing on demographic, clinical, and laboratory parameters extracted from electronic health records (EHR) of Appalachian Regional Healthcare (ARH). Among 100 patient encounters, 56 were analyzed, revealing notable sex-based differences in smoking rates and co-existing conditions, with males showing higher rates of black lung and chronic obstructive pulmonary disease.

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Silicosis in Western U.S. Metal and Nonmetal Miners, 2002-2023.

Am J Respir Crit Care Med

March 2024

Division of Environmental and Occupational Health Sciences, National Jewish Health, Denver, Colorado.

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