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Prospective validation study of a combined urine and plasma test for predicting high-grade prostate cancer in biopsy naïve men.
Scand J Urol
January 2025
Department of Urology, Odense University Hospital, Odense, Denmark; Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Objective: Early and accurate diagnosis of prostate cancer (PC) is crucial for effective treatment. Diagnosing clinically insignificant cancers can lead to overdiagnosis and overtreatment, highlighting the importance of accurately selecting patients for further evaluation based on improved risk prediction tools. Novel biomarkers offer promise for enhancing this diagnostic process.
View Article and Find Full Text PDFInvestigation and Treatment of Infertility in a Female Black Rhinoceros (Diceros bicornis).
Zoo Biol
January 2025
Taronga Conservation Society Australia, Taronga Institute of Science and Learning, Mosman New South Wales 2088, Taronga Western Plains Zoo, Dubbo, New South Wales, Australia.
A zoo-based, 11-year-old, uniparous southern black rhinoceros (Diceros bicornis minor) failed to conceive after weaning a calf. Behavioral observation and fecal progestagen monitoring confirmed irregular estrous cycles. Serial transrectal reproductive ultrasound examination revealed the cause to be recurrent anovulatory hemorrhagic follicles (AHFs).
View Article and Find Full Text PDFUltrasound super-resolution imaging for non-invasive assessment of microvessel in prostate lesion.
Cancer Imaging
January 2025
Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Background: Prostate cancer (PCa) is the leading cause of cancer-related morbidity and mortality in men worldwide. An early and accurate diagnosis is crucial for effective treatment and prognosis. Traditional invasive procedures such as image-guided prostate biopsy often cause discomfort and complications, deterring some patients from undergoing these necessary tests.
View Article and Find Full Text PDFInfluence of Regular Statin Intake on Prostate-Specific Antigen Values, Prostate Cancer Incidence and Overall Survival in a Prospective Screening Trial (ERSPC Aarau).
Cancer Med
January 2025
Department of Urology, Cantonal Hospital Aarau, Aarau, Switzerland.
Article Synopsis
- The study investigated the impact of statin use on prostate cancer (PCa) development and prostate-specific antigen (PSA) levels in a cohort of 4,314 men over nearly 10 years.
- Statin users (761 men) had significantly lower baseline and follow-up PSA levels compared to non-users, but the overall incidence of PCa was similar between the two groups, indicating statins did not reduce the risk of developing PCa.
- Additionally, statin users had a higher risk of overall mortality, suggesting that while they had lower PSA levels, statin use did not confer a protective effect against prostate cancer.
Non-invasive methods for diagnosing pregnancy in cows and their real value.
Pol J Vet Sci
December 2024
Nicolaus Copernicus University Veterinary Clinic, Szosa Bydgoska 13, 87-100 Toruń, Poland.
Proper management of cattle reproduction has a major impact on the efficiency and profitability of dairy production. Ultrasound examination and transrectal palpation or the pregnancy-associated glycoprotein (PAG) test are currently the most commonly used methods for pregnancy diagnosis. However, alternative methods to those mentioned above are constantly being sought in order to minimise stress during the examination, the cost of veterinary services and to reduce the rate of errors in pregnancy diagnosis.
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