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Background: Copeptin is a novel biomarker of potential diagnostic and prognostic value in patients with ST-elevation myocardial infarction (STEMI). This study was conducted to investigate the relationship between plasma copeptin levels at admission and final infarct size in STEMI patients.

Materials And Methods: This observational study was conducted in Sher-i-Kashmir Institute of Medical sciences, Srinagar, for a period of 1year.

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Introduction: It is well known that mitral stenosis (MS) is complicated by pulmonary hypertension (PH) of varying degrees. The hemodynamic derangement is associated with structural changes in the pulmonary vessels and parenchyma and also functional derangements. This article analyzes the pulmonary function derangements in 25 patients with isolated/predominant mitral stenosis of varying severity.

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Aim: To study interrelation of main clinico-hemodynamic parameters and levels of natriuretic peptides (NUP) in patients with hypertrophic cardiomyopathy (HCMP).

Material And Methods: We measured concentrations of N-terminal fragments of precursors of plasma brain and atrial natriuretic peptides (NT-proBNP and NT-proANP) and conducted complex echocardiographical examination in 94 patients (mean age 42.3 +/- 133.

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Lipid peroxidation, antioxidant defense and microrheological properties of blood were determined, correlated and compared with clinico-hemodynamic indices in patients with ischemic heart disease (IHD). It is shown that products of lipid peroxidation modify structure and function of red cells and platelets in IHD. A regulatory role of the antioxidant system in metabolism of lipoperoxides and peroxide damage to blood cells in IHD is shown.

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The examination of 70 postmyocardial infarction females on aftertreatment in the sanatorium demonstrated that marked cardiohemodynamic shifts correlating in severity with those of the patient's condition persisted in the early post-hospital period. Most of the patients had hypokinetic circulation, those of gravity class III delayed in forming compensatory and adaptive mechanisms of the cardiovascular system under growing muscular load. The greatest role in forming physical adaptation is attributed to peripheral hemodynamics.

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