Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF00587005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
CineECG Repolarization Gradients Predict Acute Hemodynamic Response in CRT Patients.
J Cardiovasc Electrophysiol
December 2024
Department of Cardiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Article Synopsis
- - The study investigates the effectiveness of a new ECG technique called CineECG, which visualizes heart electrical activity, in improving cardiac resynchronization therapy (CRT) for patients who don't respond well to standard treatments.
- - Researchers analyzed CineECG data from 15 patients with heart conditions under different pacing settings and found that specific movement directions in the heart's electrical signals correlate with better immediate heart performance (measured as dP/dt max).
- - The results indicate that the direction of the ST-T segment during repolarization can predict a significant improvement in heart function during CRT, suggesting that CineECG could help optimize treatment plans for patients.
Cardioprotective effects of S-equol, a soybean metabolite with estrogen activity, and role of the PI3K/Akt pathway in a male rat model of ischemic reperfusion.
Steroids
January 2025
Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi 409-3898, Japan.
Purpose: S-equol, an isoflavone metabolite with high estrogenic activity, exhibits organ-protective effects via the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway. While estrogen has cardioprotective effects against ischemia-reperfusion injury, whether S-equol shares this capability remains uncertain. This study aimed to assess the cardioprotective effects of S-equol on stunned myocardium using an isolated rat heart model and investigate the involvement of PI3K/Akt signaling pathway.
View Article and Find Full Text PDFdP/dt: An underestimated prognostic factor in large animal infarction model.
Animal Model Exp Med
November 2024
Department of Cardiology, Kaposi Moritz Teaching Hospital, Kaposvár, Hungary.
The present study aims to establish a reproducible large animal experimental unit using a minipig model to monitor cardiac function changes. A 90-min closed-chest balloon occlusion of the left anterior descending branch of the coronary artery was used to induce myocardial infarction in Pannon minipigs. To monitor the cardiac function, measurements were made by cardiac magnetic resonance imaging (cMRI), invasive pressure monitoring, and a Pulse index Continuous Cardiac Output (PiCCO) hemodynamic system at 0, 72, and 720 h during the follow-up period.
View Article and Find Full Text PDFCardioprotective effects of l-glutamine in an ischemic rat heart model.
Microvasc Res
November 2024
Department of Anesthesia, Royal Victoria Hospital, McGill University Health Centre Glen Site, Montreal, QC, Canada.
Introduction: l-glutamine has been shown to have cardioprotective effects in models of ischemia-reperfusion injury. Its potential cardioprotective effects when given before and during early reperfusion, however, have not been studied.
Methods: This study hypothesized that l-glutamine administered before and after myocardial ischemia provides better cardioprotection than when administered after ischemia only.
Human platelet lysate combined with mesenchymal stem cells pretreated with platelet lysate improved cardiac function in rats with myocardial infarction.
Sci Rep
November 2024
Gastroenterology and Hepatology Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Article Synopsis
- * The study conducted on male Wistar rats compared the effects of several treatments (HPL, PMSCs, PMSC lysate, and their combinations) on cardiac function and recovery post-MI induced by LAD ligation.
- * Results showed that treatments with HPL and PMSCs improved blood pressure and cardiac function while also increasing the presence of cardiac cell markers, indicating HPL enhances the environment for heart cell recovery and differentiation from PMSCs.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!