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A case report on renal metastasis as an unusual presentation of choriocarcinoma.
BMC Womens Health
October 2024
Department of Gynecology and Obstetrics, Development and Related Diseases of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second Hospital, Sichuan University, Chengdu, Sichuan, 610041, P.R. China.
Article Synopsis
- * The case presented involves a 27-year-old woman with symptoms like vaginal bleeding and abdominal pain, suspected to be linked to an ectopic pregnancy, but tests revealed no signs of pregnancy during surgeries.
- * After multiple treatments that failed to diagnose the issue, her hCG levels rose significantly, leading to emergency surgery and subsequent imaging that revealed suspicious lesions in her kidneys and lungs, confirming the advanced progression of the disease.
Intestinal choriocarcinoma without primary source: A diagnostic enigma.
Ulus Travma Acil Cerrahi Derg
October 2024
Department of Obstetrics and Gynecology, Manisa Celal Bayar University, Manisa-Türkiye.
Article Synopsis
- Intestinal choriocarcinoma, a rare type of cancer, was reported for the first time in a patient after an ectopic pregnancy.
- A 24-year-old woman experienced severe abdominal pain and vomiting, leading to emergency surgery that uncovered abscesses and obstructions in her small intestine, which were later diagnosed as choriocarcinoma.
- Post-surgery, PET scans indicated healing at the surgery site and showed no signs of cancer recurrence, leading to a treatment plan involving multi-agent chemotherapy.
Trophoblastic disease and choriocarcinoma.
Eur J Surg Oncol
October 2024
Department of Anatomy, Faculty of Medicine and Surgery University of Malta, Malta; Department of Pathology, Mater Dei Hospital, Malta.
Gestational trophoblastic disease (GTD) is a group of diseases associated with pregnancies that demonstrate abnormal development of trophoblastic cells. GTD includes hydatidiform moles (HM) that may continue to further develop into gestational trophoblastic neoplasms (GTN), such as choriocarcinoma (CC). Gestational CC is a malignant mass development that may arise from HM, from other (normal) pregnancies or from other gestational events (such as ectopic pregnancies).
View Article and Find Full Text PDFAtypical placental site nodules: Clinicopathologic features, management and patient outcomes in an institutional series.
Gynecol Oncol
November 2024
Division of Gynecologic Oncology, New England Trophoblastic Disease Center, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Objective: To report the New England Trophoblastic Disease Center (NETDC) experience with atypical placental site nodules (APSN).
Methods: The NETDC registry was reviewed from 2005 to 2022 and clinical data abstracted. Expert pathologists in GTD reviewed available slides with concurrent immunohistochemical analysis.
A Case of Metastatic Vulvar Choriocarcinoma Misdiagnosed as Vulvar Abscess: A Case Report.
Case Rep Obstet Gynecol
August 2024
Department of Surgical Oncology Ocean Road Cancer Institute (ORCI), P.O Box 3592 Barrack Obama Drive, Dar es Salaam, Tanzania.
Metastatic vulvar choriocarcinoma, a rare ectopic gestational trophoblastic neoplasia (GTN), often presents a diagnostic challenge due to its mimicry of other conditions, particularly in resource-limited settings. Its primary symptom is abnormal vaginal bleeding without a clear cause. Consequently, diagnosing and managing it poses difficulties for many low-resource health facilities, as evidenced by the current case.
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