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Lingual artery thrombosis as a presentation of infective endocarditis in a pregnant patient: a case report.

Eur Heart J Case Rep

January 2025

Department of Cardiology, Clínica Alemana de Santiago, Avenida Manquehue Norte #1499, 7650568 Vitacura, Chile.

Background: Infective endocarditis during pregnancy is a rare condition that compromises the health of both the mother and the foetus, presenting high rates of morbidity and mortality. The clinical manifestations of this disease are varied, with embolic phenomena being a frequent presentation.

Case Summary: We report the case of a Hispanic 37-year-old patient, at 29 weeks of pregnancy, with no known cardiovascular history, who presented with 48 h of sudden mandibular and lingual pain.

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A 75-year-old patient with a history of mitral and aortic valve replacement surgery 7 years ago, presented with progressive dyspnea. Transesophageal echocardiogram showed a mass suggestive of bioprosthetic mitral valve thrombosis. We present the investigation process using imaging, surgical findings, nuclear medicine, and histopathology that result in the diagnosis of cardiac angiosarcoma.

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Background: Unlike non-rheumatic atrial fibrillation (AF), where left atrial thrombus (LAT) is predominantly confined to the left atrial appendage (LAA), a significant proportion of LAT in rheumatic AF occurs within the left atrial cavity (LAC). However, LAC thrombosis in rheumatic AF has not been extensively studied. This study aimed to evaluate the prevalence of LAT and its subtypes and identify potential predictors of LAT.

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Percutaneous valve implantation or surgical replacement with mechanical or biological valves are standard therapies for severe valvular heart diseases. Prosthetic valve thrombosis, though rare, is a serious complication, particularly with mechanical prostheses. This study aimed to investigate the predictive value of platelet volume parameters, including mean platelet volume (MPV), platelet distribution width (PDW), and platelet-large cell ratio (P-LCR), for valvular thrombosis risk in patients undergoing valve replacement therapy.

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