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Lactational performance effects of 3-nitrooxypropanol supplementation to dairy cows: A meta-regression.

J Dairy Sci

February 2025

Department of Animal Science, The Pennsylvania State University, University Park, PA 16802. Electronic address:

A meta-regression was conducted to determine the production effects of 3-nitrooxypropanol (3-NOP) and investigate their associations with dose, dietary nutrient composition, and supplementation length in dairy cows. Forty treatment and control mean comparisons extracted from 21 studies conducted or published between 2014 to 2024 were used in the meta-regression. Response variables were DMI, milk yield (MY), ECM yield, ECM feed efficiency, BW, BW change, and concentrations of milk fat, true protein, lactose, and MUN.

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Ribosome profiling and single-cell RNA sequencing identify the unfolded protein response as a key regulator of pigeon lactation.

Zool Res

January 2025

National Key Laboratory for Swine Genetic Improvement and Germplasm Innovation, Ministry of Science and Technology of China, Jiangxi Agricultural University, Nanchang, Jiangxi 330045, China.

Pigeons and certain other avian species produce a milk-like secretion in their crop sacs to nourish offspring, yet the detailed processes involved are not fully elucidated. This study investigated the crop sacs of 225-day-old unpaired non-lactating male pigeons (MN) and males initiating lactation on the first day after incubation (ML). Using RNA sequencing, ribosome profiling, and single-cell transcriptome sequencing (scRNA-seq), we identified a significant up-regulation of genes associated with ribosome assembly and protein synthesis in ML compared to MN.

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Initial periods of life, beginning before birth and lasting until weaning are characterised by the greatest neural plasticity. Early postnatal stress causes lasting changes in a variety of behaviours as well as stress reactivity. Cow-calf contact for an extended period is believed to improve the social skills of calves and has also been linked to improved productivity of mothers.

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Perfluorooctane sulfonate (PFOS) exerts adverse effects on neuronal development in young population. Limited evidences have shown that early-life PFOS exposure holds a potential risk for developing age-related neurodegenerative diseases such as Alzheimer's disease later in life. The present study investigated the effects of lactational PFOS exposure on cognitive function using one-year-old mice.

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Objective: To assess the acceptance of multiple micronutrient supplements and current iron and folic acid supplement utilisation among pregnant and lactating women in rural Ethiopia.

Design: Community-based cross-sectional study using a mixed method.

Setting: This study was carried out in five regions (Oromia, Gambela, Sidama, SNNPR (Southern Nations, Nationalities and Peoples Region) and Somali) of Ethiopia, 2022.

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