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Clin Rheumatol
January 2025
Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou Province, China.
Objective: Rheumatoid arthritis (RA) is an autoimmune condition that causes severe joint deformities and impaired functionality, affecting the well-being and daily life of individuals. Consequently, there is a pressing demand for identifying viable therapeutic targets for treating RA. This study aimed to explore the molecular mechanisms of osteoclast differentiation in PBMC from patients with RA through transcriptome sequencing and bioinformatics analysis.
View Article and Find Full Text PDFJ Mol Model
January 2025
Escuela Superior de Física y Matemáticas, IPN S/N, Edificio 9 de la Unidad Profesional "Adolfo López Mateos", Col. Lindavista, Alc. Gustavo A. Madero, 07738, Mexico City, Mexico.
Context: "Nanostructure of graphene-reinforced with polymethyl methacrylate" (PMMA-G), and vice versa, is investigated using its molecular structure, in the present work. The PMMA-G nanostructure was constructed by bonding PMMA with graphene nanosheet in a sense to get three different configurations. Each configuration consisted of polymeric structures with three degrees of polymerization (such as monomers, dimers, and trimers polymers, respectively).
View Article and Find Full Text PDFMamm Genome
January 2025
Universidade Professor Edson Antônio Velano (UNIFENAS), Rodovia 179, Km 0, Alfenas, MG, 37132440, Brasil.
This study aimed to identify splicing quantitative trait loci (cis-sQTL) in Nelore cattle muscle tissue and explore the involvement of spliced genes (sGenes) in immune system-related biological processes. Genotypic data from 80 intact male Nelore cattle were obtained using SNP-Chip technology, while RNA-Seq analysis was performed to measure gene expression levels, enabling the integration of genomic and transcriptomic datasets. The normalized expression levels of spliced transcripts were associated with single nucleotide polymorphisms (SNPs) through an analysis of variance using an additive linear model with the MatrixEQTL package.
View Article and Find Full Text PDFCell Physiol Biochem
January 2025
Carrera de Agroindustria, Escuela Superior Politécnica Agropecuaria de Manabí Manuel Félix López, ESPAM-MFL, Calceta. 130250, Ecuador.
Background/aims: This study investigates how pH levels affect the characteristics of biopolymer films manufactured from cassava peel starch. Cassava peel starch's abundance and biodegradability make it a promising candidate for sustainable packaging. The study seeks to improve film qualities such as thickness, density, moisture content, solubility, and optical properties by altering pH levels.
View Article and Find Full Text PDFBiopolymers
March 2025
Centro de Investigación en Química Aplicada, Saltillo, Coahuila, Mexico.
Exploring new ecological and simultaneous processes to modify wood fibers (WF) by-products is a required pathway toward circular economy and sustainability. Thus, plasma-activated water (PAW) and ultrasound (U) were employed as alternative methods to modify WF in a continuous process. Such treatments promoted the etching and cavities on the WF surface that destabilized the hydrogen bonds of the hemicellulose and lignin molecules, increasing the cellulose fraction.
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