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Dental caries causes mineral loss and organic damage to teeth. Understanding caries and dentin pulp reactions is crucial for effective caries management strategies. There is a lack of knowledge regarding the microscopic and ultramicroscopic changes that occur during caries destruction and reactive changes.

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Objective: Aim: To evaluate the correlation between the mineral composition of the hard tissues of the teeth and the percentage of defects and loss of various restorative materials in permanent teeth in children living in the lowland and mountainous geographical zones of Transcarpathian region.

Patients And Methods: Materials and Methods: 1050 permanent teeth of different groups filled with different materials were studied. An ultra-microscopic examination by the method of raster electron microscopy was carried out and the mineral composition of the teeth was evaluated.

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Study of the relationships among known virulence genes, coccoid transformation and cytotoxicity of in different clinical diseases.

Virulence

December 2024

National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Article Synopsis
  • This study identifies the disconnect between known virulence genes and the infectivity of a certain strain that has infected approximately 4.4 billion people globally.
  • Researchers used whole-gene sequencing and microscopy to analyze 35 strains, observing no significant relationship between virulence genes, coccoid transformation, and cytotoxicity in various clinical cases.
  • The findings led to the development of a new virulence classification based on the strain's ability to defend and attack, though further verification of its correlation with pathogenic ability is still needed.
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Confinement-Driven Dimethyl Ether Carbonylation in Mordenite Zeolite as an Ultramicroscopic Reactor.

Acc Chem Res

October 2024

Interdisciplinary Institute of NMR and Molecular Sciences, Hubei Province for Coal Conversion and New Carbon Materials, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, P. R. China.

ConspectusThe conversion of C1 molecules to methyl acetate through the carbonylation of dimethyl ether in mordenite zeolite is an appealing reaction and a crucial step in the industrial coal-to-ethanol process. Mordenite zeolite has large 12-membered-ring (12MR) channels (7.0 × 6.

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Aim: The purpose of this study is to assess the in vitro antimicrobial and anti-biofilm effects of the anti-protozoal agent tafenoquine (TAF) on Enterococcus and elucidate its underlying mode of action.

Methods And Results: The present work investigated the susceptibility of TAF on 3 type strains and 11 clinical isolates of enterococci. The results indicated that TAF exhibited powerful antimicrobial activity against both of Enterococcus faecalis and Enterococcus faecium with minimum inhibitory and bactericidal concentrations ranging from 8 to 16 µg ml-1.

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