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Epidemiological cut-off values for Vibrio parahaemolyticus calculated from minimal inhibitory concentration data generated at 35 and 28°C.
Dis Aquat Organ
December 2024
Centre for Environment, Fisheries and Aquaculture Science, Weymouth DT4 8UB, UK.
Article Synopsis
- The study aimed to establish epidemiological cut-off values for the minimum inhibitory concentrations (MICs) of 10 antimicrobial agents against the bacteria Vibrio parahaemolyticus using standardized testing methods.
- Eight laboratories conducted broth microdilution tests at two different temperatures (35°C and 28°C) to assess the effect of incubation temperature on MIC values, finding that many values were consistent across both temperatures.
- The generated data will be submitted to the Clinical and Laboratory Standards Institute to help set international standards for interpreting antimicrobial susceptibility tests for this species.
Direct and indirect photolysis of oxolinic acid in surface waters and its inhibition by antioxidant effects.
Water Res
March 2025
Dipartimento di Chimica, Università di Torino, Torino, Italy.
Article Synopsis
- Oxolinic acid is a quinolone antibiotic used in aquaculture, raising environmental concerns as it can enter water bodies from aquaculture effluents.
- The study focused on the reactivity of its anionic form through direct and indirect photolysis, determining how it reacts with various radicals produced in water.
- Results indicate that OxA is quite photoreactive, especially with HO and CO radicals, but its degradation can be inhibited by compounds like phenol, with predicted half-lives of a few days in both fresh and seawater mainly due to direct photolysis.
Effect of non-antibiotic factors on conjugative transfer of antibiotic resistance genes in aquaculture water.
J Hazard Mater
February 2025
NUS Environmental Research Institute, National University of Singapore, 5A Engineering Drive 1, Singapore 117411, Singapore; Department of Civil & Environmental Engineering, National University of Singapore, 1 Engineering Drive 2, Singapore 117576, Singapore. Electronic address:
Aquaculture water with antibiotic resistance genes (ARGs) is escalating due to the horizontal gene transfer. Non-antibiotic stressors specifically found, including those from fishery feed and disinfectants, are potential co-selectors. However, the mechanisms underlying this process remains unclear.
View Article and Find Full Text PDFAntimicrobial Susceptibility and Local Epidemiological Cut-Off Values of Vibrio anguillarum Isolated From Fish Farms in Turkey.
J Fish Dis
February 2025
Laboratorio de Patología de Organismos Acuáticos y Biotecnología Acuícola, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Viña del Mar, Chile.
Studies on preventing antimicrobial resistance in aquaculture emphasise the need to responsibly and prudently use antimicrobials, selecting those most effective in controlling and/or reducing mortalities caused by vibriosis. In this study, the distribution of the antimicrobial susceptibility of 28 Vibrio anguillarum isolates from Turkish fish farms was determined using the broth microdilution minimum inhibitory concentration (MIC) test according to the Clinical and Laboratory Standards Institute (CLSI) guideline. The epidemiological cut-off (CO) values of the V.
View Article and Find Full Text PDFComparison of Resistance Acquisition and Mechanisms in Erwinia amylovora against Agrochemicals Used for Fire Blight Control.
Plant Pathol J
October 2024
Division of Biotechnology, Jeonbuk National University, Iksan 54596, Korea.
Article Synopsis
- Agrochemicals with antibiotics have been used to combat fire blight in Korea since 2015, but the effectiveness of these antibiotics is declining due to increased resistance in the pathogen Erwinia amylovora.
- The study revealed that exposure to different antibiotics led to specific gene mutations in the pathogen, significantly raising the minimum inhibitory concentration (MIC) required to control it.
- The findings indicate that using mixed antibiotics may slow resistance development but could still lead to multidrug-resistant strains, highlighting the need for careful management to prevent further resistance.
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