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Measurement of multidifferential cross sections for dijet production in proton-proton collisions at .
Eur Phys J C Part Fields
January 2025
A measurement of the dijet production cross section is reported based on proton-proton collision data collected in 2016 at by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of up to 36.3 . Jets are reconstructed with the anti- algorithm for distance parameters of and 0.
View Article and Find Full Text PDFExperimental and GEANT4 Simulated FEPE of NaI(Tl) Detector for Linear Sources.
Biomed Phys Eng Express
January 2025
Physics and Applied Mathematics, Pakistan Institute of Engineering and Applied Sciences, Qau, Islamabad, Islamabad, 44000, PAKISTAN.
The current study investigated the geometry, design and solid angle impacts on full energy peak efficiency (FEPE) of NaI(Tl) detectors for a line source. A line source is fabricated using 99mTc solution filled in a borosilicate glass tube of inner diameter 3 mm, tube wall thickness 2.5 mm and length 12.
View Article and Find Full Text PDFComparison of ZnS(Ag) Scintillator and Proportional Counter Tube for Alpha Detection in Thin-Layer Chromatography.
Pharmaceuticals (Basel)
December 2024
Department of Nuclear Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstr. 74, 01307 Dresden, Germany.
(1) : Targeted alpha therapy is an emerging field in nuclear medicine driven by two advantages: overcoming resistance in cancer-suffering patients to beta therapies and the practical application of lower activities of Pb- and Ac-labelled peptides to achieve the same doses compared to beta therapy due to the highly cytotoxic nature of alpha particles. However, quality control of the Pb/Ac-radiopharmaceuticals remains a challenge due to the low activity levels used for therapy (100 kBq/kg) and the formation of several free daughter nuclides immediately after the formulation of patient doses; (2) : The routine alpha detection on thin-layer chromatograms (TLC) of Pb- and Ac-labelled peptides using a MiniScanPRO+ scanner combined with an alpha detector head was compared with detection using an AR-2000 scanner equipped with an open proportional counter tube. Measurement time, resolution and validity were compared for both scanners; (3) : For Ac, the quality control values of the radiochemical purity (RCP) were within the acceptance criteria 2 h after TLC development, regardless of when the TLC probe was taken.
View Article and Find Full Text PDFRealistic total-body J-PET geometry optimization: Monte Carlo study.
Med Phys
January 2025
Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Kraków, Poland.
Background: Total-body (TB) Positron Emission Tomography (PET) is one of the most promising medical diagnostics modalities, opening new perspectives for personalized medicine, low-dose imaging, multi-organ dynamic imaging or kinetic modeling. The high sensitivity provided by total-body technology can be advantageous for novel tomography methods like positronium imaging, demanding the registration of triple coincidences. Currently, state-of-the-art PET scanners use inorganic scintillators.
View Article and Find Full Text PDFCharacterization of cell membrane fragments containing muscle type nAChR from Tetronarce californica after preparation using high pressure homogenization.
Toxicol Lett
January 2025
Bundeswehr Institute for Pharmacology and Toxicology, Neuherbergstraße 11, Munich 80937, Germany. Electronic address:
The nicotinic acetylcholine receptor (nAChR) is a pentameric ligand-gated ion channel (pLGIC) commonly used as a model for receptors belonging to the Cys-loop superfamily. Members of pLGICs are standardly used in numerous toxicological investigations e.g.
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