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An autopsy case with tubular obstruction by impacted swollen blebs due to ischemic acute kidney injury.
BMC Nephrol
January 2025
Department of Nephrology, Japan Community Healthcare Organization Sendai Hospital, 981-3281, Sendai, Miyagi, Japan.
Background: Oliguric acute kidney injury (AKI) is one of the critical conditions which needs emergent treatment due to the lack of the capacity of excreting toxins and fluids, and plasma membrane bleb formation is considered as one of the characteristic morphologic alterations in ischemic AKI in both animal models and human. We present here an autopsy case with clear electron microscopy images capturing a definitive instance of blebbing in ischemic AKI.
Case Presentation: A 66-year-old man was admitted for oliguric AKI with nephrotic syndrome (NS).
Examining physical and technical performance among youth basketball national team development program players: a multidimensional approach.
Sci Rep
January 2025
Department of Sport Games, Józef Piłsudski University of Physical Education in Warsaw, Marymoncka 34, Warsaw, 00-968, Poland.
This study aimed to examine and compare the anthropometric profiles, motor skills, game-related abilities, and functional capacities of under-15 (U-15) and under-16 (U-16) male basketball players, evaluate the impact of maturity offset, and predict performance across physical and sport-specific domains. A total of 234 athletes participated in a comprehensive test battery, assessing morphological (height, mass, standing reach), physical (sprinting, agility, jump height, endurance), technical (jump shot, free throws, dribbling), and functional movement screen variables. The U-16 group outperformed U-15 players in physical characteristics and jump height.
View Article and Find Full Text PDFThe developmental and genetic basis of male genitalia evolution in Drosophilids.
Curr Opin Insect Sci
January 2025
Department of Genetics and Developmental Biology, The Rappaport Faculty of Medicine and Research Institute, Technion - Israel Institute of Technology, Haifa 3109601, Israel. Electronic address:
Reproductive organs are among the most variable and rapidly evolving structures in the animal kingdom, probably due to sexual selection. In insects, the diverse morphology of male genitalia is often one of the few visible characteristics that can reliably distinguish closely related species, making it crucial for taxonomic classification. Consistent with this, males of the model organism Drosophila melanogaster and its closely related species display remarkable variations in genital morphology.
View Article and Find Full Text PDFComparative assessment of microplastic ingestion among deep sea decapods: distribution analysis in Sardinian and Catalan waters.
Environ Res
January 2025
Dipartimento di Scienze della Vita e dell'Ambiente, Università degli Studi di Cagliari, Via Tommaso Fiorelli 1, 09126 Cagliari, Italy; Departament de Biologia Animal, Biologia Vegetal i Ecologia, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, 08193 Barcelona, Spain. Electronic address:
Microplastic (MP) pollution is a widespread and concerning environmental issue. The benthic layer is known as one of the major accumulation sinks, yet knowledge gaps still remain in describing the interactions of its biota with MPs. This work represents a comprehensive comparative analysis of MP ingestion in the four deep-sea crustacean decapods Aristeus antennatus (Risso, 1816), Aristaeomorpha foliacea (Risso, 1827), Nephrops norvegicus (Linnaeus, 1758) and Parapenaeus longirostris (Lucas, 1846) sampled from two distinct regions of the Mediterranean Sea in order to underscore the species-specific characteristics driving their MP ingestion variations.
View Article and Find Full Text PDFNOTCH1, 2, and 3 receptors enhance osteoblastogenesis of mesenchymal C3H10T1/2 cells and inhibit this process in preosteoblastic MC3T3-E1 cells.
Differentiation
January 2025
Área de Bioquímica y Biología Molecular, Departamento de Química Inorgánica, Orgánica y Bioquímica, Facultad de Medicina/IB-UCLM/Unidad de Biomedicina, Universidad de Castilla-La Mancha/CSIC, Albacete, Spain. Electronic address:
Osteoblastogenesis is governed by complex interplays among signaling pathways, which modulate the expression of specific markers at each differentiation stage. This process enables osteoblast precursor cells to adopt the morphological and biochemical characteristics of mature bone cells. Our study investigates the role of NOTCH signaling in osteogenesis in MC3T3-E1 and C3H10T1/2 cell lines.
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