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Evaluation of the Therapeutic Potential of the Methanolic Extract and Fractions of Datura stramonium in Paracetamol-intoxicated Rabbits.
Curr Pharm Des
January 2025
Department of Horticulture and Life Science, Yeungnam University, Republic of Korea.
Introduction: Datura stramonium (DS) possesses strong medicinal and therapeutic potential but has been rarely evaluated in this context.
Methods: The present study was intended to evaluate the antioxidant, hepatoprotective, and nephroprotective potential of the crude methanolic leaf extract and ethyl acetate, chloroform, n-hexane, and aqueous fractions of DS in paracetamol-intoxicated rabbits. Paracetamol (2 g/Kg BW) was applied to induce liver and kidney injury in rabbits while the methanolic extract and fractions of DS were applied in the dose range of 150 mg/Kg to 300 mg/Kg body weight for 21 days.
Pediatric Toxidrome Simulation Curriculum: Jimson Weed Toxicity.
MedEdPORTAL
August 2023
Associate Professor, Division of Emergency Medicine, Department of Pediatrics, University of Washington School of Medicine.
Introduction: Jimson weed is a poisonous plant containing tropane alkaloids that can cause anticholinergic toxicity. Recognition of anticholinergic toxidrome is important for prevention and management of potentially life-threatening complications of severe toxicity, including dysrhythmia and seizure.
Methods: Designed for pediatric emergency medicine (PEM) fellows, this simulation featured a 15-year-old female presenting to the emergency department (ED) with agitation and hallucinations.
[Deliberate intoxication with Datura Stramonium, a rare cause of confusion].
Soins Gerontol
November 2023
Département de médecine gériatrique, centre hospitalier de Rouen, 37, boulevard Gambetta, 76000 Rouen, France; Université de Rouen Normandie, Inserm U1096, 76000 Rouen, France. Electronic address:
Many drugs can be responsible for this syndrome. Although it remains rare, poisoning by Datura Stramonium should be considered in the event of anticholinergic syndrome in the elderly, particularly in the event of anticholinergic manifestations.
View Article and Find Full Text PDFGrowing your own food is like printing money, don't let it make you mad as a hatter.
Clin Chem Lab Med
May 2023
Department of Intensive Care, AZ Sint-Lucas, Ghent, Belgium.
Barcoding High Resolution Melting (Bar-HRM) enables the discrimination between toxic plants and edible vegetables prior to consumption and after digestion.
J Food Sci
September 2022
Institute of Applied Biosciences, CERTH, Thessaloniki, Greece.
The consumption of poisonous plants can lead to serious health problems or even casualties due to various factors, including easy access to poisonous plants due to their common distribution, co-occurrence and resemblance with edible plants, and the lack of regulation in the food product supply chain. Clinical diagnosis of intoxications usually relies on the availability of the plant consumed by the patient and on the morphology of the plant parts found in the patient's stomach. Therefore, given the fragmented nature of ingested plant material, species identification may face serious difficulties, can be inaccurate, and time-consuming.
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