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Does Systematic Use of Small Doses of Vitamin D Have Anti-Inflammatory Effects and Effectively Correct Deficiency Among Healthy Adults?
Nutrients
January 2025
Department of Neurology, Faculty of Health Sciences in Katowice, Medical University of Silesia, 40-635 Katowice, Poland.
Background: Calcitriol, beyond its well-established role in calcium and phosphate homeostasis, contributes to immunological processes. No known vitamin D dosage regimen effectively corrects the deficiency while accounting for immunoregulatory effects. Therefore, the purpose of this assessment was to determine whether regular administration of low doses of vitamin D might correct deficiency and have immunoregulatory effects.
View Article and Find Full Text PDFEnhancing Polylactic Acid (PLA) Performance: A Review of Additives in Fused Deposition Modelling (FDM) Filaments.
Polymers (Basel)
January 2025
Materials Engineering and Welding Department, Transilvania University of Brasov, 500036 Brasov, Romania.
This review explores the impact of various additives on the mechanical properties of polylactic acid (PLA) filaments used in Fused Deposition Modeling (FDM) 3D printing. While PLA is favored for its biodegradability and ease of use, its inherent limitations in strength and heat resistance necessitate enhancements through additives. The impact of natural and synthetic fibers, inorganic particles, and nanomaterials on the mechanical properties, printability, and overall functionality of PLA composites was examined, indicating that fiber reinforcements, such as carbon and glass fibers, significantly enhance tensile strength and stiffness, while natural fibers contribute to sustainability but may compromise mechanical stability.
View Article and Find Full Text PDFEcometabolomics of Loggerhead Sea Turtles (): The Impact of Age on Metabolomic Profiles.
Int J Mol Sci
January 2025
Department of Animal and Veterinary Sciences, Aarhus University, Blichers Alle 20, DK-8830 Tjele, Denmark.
To investigate the impact of age on the metabolomic profile of loggerhead sea turtles (), this study analyzed 100 plasma samples of individuals across two age groups-50 post-hatchlings and 50 juveniles-from various locations along the Mediterranean coastline. Both targeted and untargeted metabolomic analyses were performed on the samples. Our results demonstrated a significant age-related effect on the metabolomic profiles in both analyses.
View Article and Find Full Text PDFEvaluation of Individual Cardiovascular Risk in Pre-Dialysis CKD Patients by Using the Ratio of Calcium-Phosphorus Product to Estimated Glomerular Filtration Rate (Ca × P/eGFR).
Biomedicines
January 2025
Hemodialysis Unit, St. Marina Hospital, 5800 Pleven, Bulgaria.
Background: Chronic kidney disease (CKD) patients have an increased risk of cardiovascular disease (CVD), necessitating effective risk assessment methods. This study evaluates the calcium-phosphorus product (Ca × P) to estimated glomerular filtration rate (Ca × P/eGFR) ratio as a potential biomarker for predicting CV risk in pre-dialysis CKD patients.
Methods: Eighty-four CKD patients in stages G1-G4, according to the KDIGO criteria, were classified into CVD ( = 43) and non-CVD ( = 41) groups.
Abiotic Stress-Induced Chloroplast and Cytosolic Ca Dynamics in the Green Alga Chlamydomonas reinhardtii.
Plant Cell Environ
January 2025
Department of Biotechnology, University of Verona, Verona, Italy.
Calcium (Ca)-dependent signalling plays a well-characterised role in the perception and response mechanisms to environmental stimuli in plant cells. In the context of a constantly changing environment, it is fundamental to understand how crop yield and microalgal biomass productivity are affected by external factors. Ca signalling is known to be important in different physiological processes in microalgae but many of these signal transduction pathways still need to be characterised.
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