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A RETROSPECTIVE STUDY COMPARING THE SAFETY OF KETAMINE-MEDETOMIDINE AND TILETAMINE-ZOLAZEPAM-MEDETOMIDINE FOR CHEMICAL RESTRAINT OF CAPTIVE .
J Zoo Wildl Med
March 2025
The Royal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire, AL9 7TA, United Kingdom.
Chemical restraint, whether remote via dart or via hand injection is essential for many veterinary procedures in captive and wild . but carries risk both to the animal and staff involved. Anecdotal patient safety concerns have been raised for the use of Tiletamine-Zolazepam (TZ), particularly in tigers, that have since been disputed.
View Article and Find Full Text PDFEffect of intraoperative intravenous esketamine on postoperative delirium in older patients undergoing hip fracture surgery: protocol for a randomised, double-blind, placebo-controlled trial.
BMJ Open
March 2025
Department of Anesthesiology, Chengdu Integrated TCM & Western Medicine Hospital, Chengdu, Sichuan, China
Introduction: Postoperative delirium (POD) is a common complication after hip fracture surgery in older patients. Esketamine may be beneficial in alleviating the occurrence of POD. Our trial aim is to investigate whether the intravenous administration of esketamine can improve POD in older patients undergoing surgery for hip fracture.
View Article and Find Full Text PDFEffect of intravenous esketamine on postoperative sleep disturbance, anxiety, and depression in elderly patients undergoing laparoscopic abdominal surgery: a randomized controlled trial.
BMC Geriatr
March 2025
Department of Anesthesiology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, No. 15 Jiefang Road, Fancheng District, Xiangyang City, Hubei Province, 441000, P.R. China.
Background: The population of elderly individuals undergoing surgical procedures is increasing, necessitating effective postoperative management strategies. Postoperative sleep disturbance, anxiety, and depression are significant contributors to overall recovery in this demographic, especially following laparoscopic abdominal surgery.
Methods: This study included 200 records of elderly patients undergoing laparoscopic abdominal surgery.
Is the Subthalamic Nucleus Sleeping Under Nitrous Oxide-Ketamine General Anesthesia?
Eur J Neurosci
March 2025
Department of Neurosurgery, Sheba Medical Center, Ramat Gan, Israel.
Nitrous oxide is a common gaseous anesthetic used in a wide range of medical procedures due to its desirable combination of anesthetic and analgesic properties. Deep brain stimulation surgery, a well-established treatment for movement disorders like Parkinson's disease, often requires precise microelectrode recordings of the awake brain's electrical signals for optimal results. However, the influence of anesthetics on these brain signals remains a critical consideration.
View Article and Find Full Text PDFEffect of esketamine on postoperative sleep disturbance in patients undergoing spinal surgery: a study protocol for a randomised, double-blinded, placebo-controlled clinical trial.
BMJ Open
March 2025
Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Introduction: Postoperative sleep disturbance (PSD) is a common complication after spinal surgery that can be related to postsurgical pain, perioperative anxiety and depression. Recent studies have shown that esketamine may improve sleep disturbance after surgery; however, it remains unclear whether intraoperative infusion of esketamine can improve the postoperative sleep quality of patients undergoing spinal surgery.
Methods And Analysis: This is a protocol for a randomised, double-blinded, placebo-controlled clinical trial to evaluate the effect of esketamine on PSD in patients undergoing spinal surgery.
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