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Long-term results of lymphedema treatment with Combined lymph node transfer and collagen scaffolds: An Observational Study.
JPRAS Open
March 2025
Department of Plastic Surgery, Aristotle University of Thessaloniki, School of Medicine, Papageorgiou General Hospital, Thessaloniki, 54603, Greece.
Aim: Vascularized lymph node transfer (VLNT) accelerates growth factor secretion, lymphatic endothelial cell migration toward the interstitial flow and lymphagiogenesis in a multidirectional pattern. Our observational study aimed to examine the hypothesis that nanofibrillar collagen scaffolds (NCS) combined with VLNT can provide guided lymphagiogenesis creating long-lasting lymphatic pathways.
Methods: Twenty-four patients (21 female, 3 male) underwent a lymphatic microsurgery for upper ( = 11) or lower ( = 13) limb secondary lymphedema and completed at least 18 months follow-up were selected and equally divided in 2 groups; Group-A underwent VLNT, Group-B underwent combined VLNT and NCS procedure.
Magnetophononics and the chiral phonon misnomer.
PNAS Nexus
January 2025
The Harrison M. Randall Laboratory of Physics, University of Michigan, Ann Arbor, MI 48109-1040, USA.
The direct, ultrafast excitation of polar phonons with electromagnetic radiation is a potent strategy for controlling the properties of a wide range of materials, particularly in the context of influencing their magnetic behavior. Here, we show that, contrary to common perception, the origin of phonon-induced magnetic activity does not stem from the Maxwellian fields resulting from the motion of the ions themselves or the effect their motion exerts on the electron subsystem. Through the mechanism of electron-phonon coupling, a coherent state of circularly polarized phonons generates substantial non-Maxwellian fields that disrupt time-reversal symmetry, effectively emulating the behavior of authentic magnetic fields.
View Article and Find Full Text PDFGenetic association of lipid and lipid-lowing drug targets with uterine fibroids.
Heliyon
January 2025
Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, 213000, China.
Objective: Observational studies suggest that blood lipids are a risk factor for uterine fibroids (UFs) and that lipid-lowering drugs are beneficial for the treatment and prevention of UF; however, the conclusions are inconsistent. We aimed to determine the causal effects of lipids and lipid-lowering drugs on UFs using Mendelian randomization (MR).
Methods: Genetic variants from genome-wide association studies (GWAS) of lipid traits and variants in genes encoding lipid-lowering drug targets were extracted, and two independent UF GWAS were set as the outcome.
Enhanced Spontaneous Emission Rate and Luminescence Intensity of CsPbBr Quantum Dots Using a High- Microdisk Cavity.
J Phys Chem Lett
January 2025
State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics, School of Physics, Peking University, Beijing 100871, China.
Perovskite quantum dots (QDs) are high-efficiency optoelectronic materials attracting great interest, but further improvement in the luminescence efficiency is crucial for their application. In this work, we enhance both the spontaneous emission rate and the photoluminescence (PL) intensity of CsPbBr QDs by coupling them to a high quality () factor SiO microdisk cavity. Compared to conventional metal plasmonic cavities, the dielectric cavity structure suppresses the effects of quenching and energy transfer, which could introduce complex fluctuations and nonradiative decays.
View Article and Find Full Text PDFImmune evasion through mitochondrial transfer in the tumour microenvironment.
Nature
January 2025
Division of Cell Therapy, Chiba Cancer Center Research Institute, Chiba, Japan.
Cancer cells in the tumour microenvironment use various mechanisms to evade the immune system, particularly T cell attack. For example, metabolic reprogramming in the tumour microenvironment and mitochondrial dysfunction in tumour-infiltrating lymphocytes (TILs) impair antitumour immune responses. However, detailed mechanisms of such processes remain unclear.
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