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Does the Heart Fall Asleep?-Diurnal Variations in Heart Rate Variability in Patients with Disorders of Consciousness.
Brain Sci
March 2022
Laboratory for Sleep, Cognition and Consciousness Research, Department of Psychology, University of Salzburg, 5020 Salzburg, Austria.
The current study investigated heart rate (HR) and heart rate variability (HRV) across day and night in patients with disorders of consciousness (DOC). We recorded 24-h electrocardiography in 26 patients with DOC (i.e.
View Article and Find Full Text PDFNeuropathology of prolonged unresponsive wakefulness syndrome after blunt head injury: review of 100 post-mortem cases.
Brain Inj
March 2014
Institute of Clinical Neurobiology, Medical University Vienna, Kenyongasse 18, Vienna, Austria.
Objectives: Recently, 'unresponsive wakefulness syndrome' (UWS) was coined for challenging conditions previously termed vegetative state or apallic syndrome.
Materials And Methods: In a post-mortem series of 630 patients who sustained a blunt traumatic brain injury, 100 (59 men and 41 women, aged 5-86 years; 77% traffic accidents, 23% falls and others) showed various disorders of consciousness which were compared with neuropathology with focus on brainstem lesions.
Results: In the total autopsy series (n = 630), the incidence of cortical contusions, diffuse axonal injury (DAI) and intracranial haemorrhages was 41, 55 and 73%, respectively, of diencephalic, hypothalamic and hippocampal lesions 62% each, brainstem lesions 92%.
Acute consciousness disorders in intensive care medicine - value of its grading for prognostic conclusion.
Neuro Endocrinol Lett
July 2012
Department of Anaesthesiology and Intensive Care Medicine and Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital Martin, Armed Forces Academy of General M. R. Štefánik, Liptovský Mikuláš, Slovak Republic.
Objectives: To understand consciousness we have to understand the mechanism of its function, which is to effectively organize sensory inputs from our environment. Consciousness is the basic, essential outcome of the process of organizing these sensory inputs, resulting in cognitive, mental, emotional, executive, instinctual or other marginally aware states. This reciprocal process of the CNS implies that organization is an act, which precedes consciousness, i.
View Article and Find Full Text PDFThe vegetative state--a syndrome in search of a name.
J Med Life
February 2012
Medical Faculty University Muenster, Cerebprotect Foerderverein für Frührehabilitation eV, 48155 Muenster, Germany.
In 2002, Bryan Jennett chose the caption "A syndrome in search of a name" for the first chapter of his book "The vegetative state--medical facts, ethical and legal dilemmas", which, in summary, can be taken as his legacy. Jennett coined the term "VegetativeState" (VS), which became the preferential name for the syndrome of wakeful unresponsiveness in the English literature, with the intention to specify the concern and dilemmas in connection with the naming "vegetative", "persistent" and "permanent". In Europe, Apallic Syndrome (AS) is still in use.
View Article and Find Full Text PDFNeuroethics with regard to treatment limiting and withdrawal of nutrition and hydration in long lasting irreversible full state apallic syndrome and minimal conscious state.
J Med Life
February 2010
Medical Faculty University Münster, Frauenburgstrasse 32, D-48155 Münster.
Introduction: Epidemiology in Europe shows constantly increasing figures for the Apallic Syndrome (AS)/Vegetative State (VS) as a consequence of advanced rescue, emergency services, intensive care treatment after acute brain damage, and high standard activating home nursing for completely dependent end stage cases secondary to progressive neurological disease. Management of patients in irreversible apallic syndrome has been the subject of sustained scientific and moral-legal debate over the last decade.
Methods: Neuroethics coming more and more into consideration when neurological societies address key issues relating to AS/VS prevalence and quality management.
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