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Empathy and helping: the role of affect in response to others' suffering.
Sci Rep
January 2025
Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Decades of research hold that empathy is a multifaceted construct. A related challenge in empathy research is to describe how each subcomponent of empathy uniquely contributes to social outcomes. Here, we examined distinct mechanisms through which different components of empathy-Empathic Concern, Perspective Taking, and Personal Distress-may relate to prosociality.
View Article and Find Full Text PDFA forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance.
Dev Cell
January 2025
Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:
Distinguishing tumor maintenance genes from initiation, progression, and passenger genes is critical for developing effective therapies. We employed a functional genomic approach using the Lazy Piggy transposon to identify tumor maintenance genes in vivo and applied this to sonic hedgehog (SHH) medulloblastoma (MB). Combining Lazy Piggy screening in mice and transcriptomic profiling of human MB, we identified the voltage-gated potassium channel KCNB2 as a candidate maintenance driver.
View Article and Find Full Text PDFInvestigating the relationship between goal orientation, self-efficacy, positive emotionality, and affective engagement among Chinese students.
Acta Psychol (Amst)
January 2025
School of Marxism, Southwest Jiaotong University Hope College, Chengdu 610400, China; Health and Rehabilitation College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 611137, China. Electronic address:
This study delved into the complex interplay between self-efficacy, achievement goals, positive emotions, and affective engagement among university students in China. To achieve this, a stratified random sampling technique was employed, resulting in a sample of 391 students from four geographically distinct universities across China. The data collection relied on self-reported questionnaires that measured academic self-efficacy, goal orientation (specifically focusing on mastery versus performance goals), positive emotions, and various aspects of affective engagement, including enjoyment, satisfaction, and interest in learning.
View Article and Find Full Text PDFIncorporating Multimodal Directional Interpersonal Synchrony into Empathetic Response Generation.
Sensors (Basel)
January 2025
Faculty of Engineering, University of Toyama, Toyama 930-8555, Japan.
This study investigates how interpersonal (speaker-partner) synchrony contributes to empathetic response generation in communication scenarios. To perform this investigation, we propose a model that incorporates multimodal directional (positive and negative) interpersonal synchrony, operationalized using the cosine similarity measure, into empathetic response generation. We evaluate how incorporating specific synchrony affects the generated responses at the language and empathy levels.
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