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Explanatory models and animal health-seeking behavior for East Coast fever in rural Kenya: an ethnographic study.
Front Vet Sci
September 2024
Department of Anthropology, Gender and African Studies, University of Nairobi, Nairobi, Kenya.
Introduction: Explanatory models of disease focus on individuals' and groups' understandings of diseases, revealing a disconnect between livestock keepers and animal health providers. Animal health providers rely on models grounded in their veterinary training and experience. At the same time, livestock keepers may construct models based on traditional knowledge and their lived experience with East Coast fever in their cattle herds.
View Article and Find Full Text PDFCommunity empowerment through participation in a tsetse control project in the Democratic Republic of Congo.
PLOS Glob Public Health
June 2023
Epidemiology, Pedro Kouri Institute of Tropical Medicine Center for Diagnostic and Reference Research, La Habana, Cuba.
Gambiense Human African Trypanosomiasis (g-HAT) is a neglected tropical disease caused by trypanosomes transmitted by tsetse flies. In 2017, a pilot community-based project was launched in three villages in DRC with the overall goal of empowering community members to control tsetse using Tiny Targets which attract and kill tsetse. In this paper, we assess the community participation process in these three pilot villages over >4 years and evaluate to what extent this resulted in the empowerment of communities.
View Article and Find Full Text PDFCyclic AMP signalling and glucose metabolism mediate pH taxis by African trypanosomes.
Nat Commun
February 2022
Institute of Cell Biology, University of Bern, Bern, Switzerland.
The collective movement of African trypanosomes on semi-solid surfaces, known as social motility, is presumed to be due to migration factors and repellents released by the parasites. Here we show that procyclic (insect midgut) forms acidify their environment as a consequence of glucose metabolism, generating pH gradients by diffusion. Early and late procyclic forms exhibit self-organising properties on agarose plates.
View Article and Find Full Text PDFVectorBase.org updates: bioinformatic resources for invertebrate vectors of human pathogens and related organisms.
Curr Opin Insect Sci
April 2022
Department of Biological Sciences, Eck Institute for Global Health, University Notre Dame, Notre Dame, IN 46556, USA. Electronic address:
Article Synopsis
- VectorBase.org is a free online platform within the VEuPathDB Bioinformatics Resource Center that offers extensive multi-omics and population biology data focused on arthropod vectors and invertebrates relevant to human health.
- It features genomic data from various insects and a snail intermediate host, and provides user-friendly tools like the Search Strategy system and MapVEu for data exploration without needing programming skills.
- Users can also upload and analyze their own data, such as transcriptomic sequences, and compare their findings with publicly available datasets within the platform.
Experiences of the one-health approach by the Uganda Trypanosomiasis Control Council and its secretariat in the control of zoonotic sleeping sickness in Uganda.
Parasite Epidemiol Control
November 2020
Coordinating Office for the Control of Trypanosomiasis in Uganda (COCTU), P.O Box 16345, Wandegeya, Kampala, Uganda.
Elimination of sleeping sickness from endemic countries like Uganda is key if the affected communities are to exploit the potential of the available human and livestock resources (production and productivity). , the parasite that causes acute sleeping sickness in humans, is transmitted by tsetse flies and co-exists in non-human animal reservoirs. Uganda by Act of Parliament in 1992 decided to handle the complex approach to control of sleeping sickness and animal trypanosomiasis by establishing the Uganda Trypanosomiasis Control Council (UTCC) and its secretariat the Coordinating Office for the Control of Trypanosomiasis in Uganda (COCTU).
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