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Sex and APOE genotype modulate neuropsychological profile and depression in temporal lobe epilepsy.
Front Neurosci
January 2025
Institute for Biomedical Research and Innovation (IRIB), Italian National Research Council (CNR), Cosenza, Italy.
Introduction: Temporal lobe epilepsy is the most common form of focal epilepsy, often associated with cognitive impairments, particularly in memory functions, and depression. Sex and APOE ε4 genotype play a crucial role in modulating cognitive outcomes and depression in various neurological conditions like Alzheimer's disease. However, the combined effects of APOE genotype and sex on cognitive performance and depression in temporal lobe epilepsy have not been previously investigated.
View Article and Find Full Text PDFExploring the influence of pregnancy on cognitive function in women: a systematic review.
BMC Pregnancy Childbirth
January 2025
Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
Background: Pregnancy has been increasingly recognized for its potential impact on cognitive function influenced significantly by hormonal fluctuations such as estrogen and progesterone. However, the findings from research in this area remain debated, often varying with individual factors and pregnancy trimesters.
Objective: This study aims to systematically review existing literature and empirical research to better understand the phenomenon known as "pregnancy brain" and its association with cognitive change.
Putting the prime in priming: Using prime processing behavior to predict target structural processing.
Psychon Bull Rev
January 2025
University of California, Santa Barbara, CA, USA.
Structural priming effects are widespread and heavily relied upon to assess structural representation and processing. Whether these effects are caused by error-driven implicit learning, residual activation, a combination of these, or some other learning mechanism remains to be established. The current study used preexisting data and a novel data analysis approach that links processing at the prime to later processing at the target to better understand the nature of structural priming.
View Article and Find Full Text PDFCerebellar Development and the Burden of Prematurity.
Cerebellum
January 2025
Department of Pediatrics, Division of Neonatology, Willem-Alexander Children's Hospital, Leiden University Medical Center, Utrecht, the Netherlands.
The role of the cerebellum in the neurodevelopmental outcomes of preterm infants has often been neglected. However, accumulating evidence indicates that normal cerebellar development is disrupted by prematurity-associated complications causing cerebellar injury and by prematurity itself. This hampers not only the normal development of motor skills and gait, but also cognitive, language, and behavioral development, collectively referred to as "developmental cognitive affective syndrome.
View Article and Find Full Text PDFMigration of Health Workers and Its Impacts on the Nigerian Health Care Sector: Protocol for a Scoping Review.
JMIR Res Protoc
January 2025
Department of Medicine and Optometry, eHealth Institue, Linnaeus University, Kalmar, Sweden.
Background: Health worker migration from Nigeria poses significant challenges to the Nigerian health care sector and has far-reaching implications for health care systems globally. Understanding the factors driving migration, its effects on health care delivery, and potential policy interventions is critical for addressing this complex issue.
Objective: This study aims to comprehensively examine the factors encouraging the emigration of Nigerian health workers, map out the effects of health worker migration on the Nigerian health system, document the loss of investment in health training and education resulting from migration, identify relevant policy initiatives addressing migration, determine the effects of Nigerian health worker migration on destination countries, and identify the benefits and demerits to Nigeria of health worker migration.
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