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Gastrointestinal Manifestations of Sarcoidosis: A State-of-the-Art, Comprehensive Review of the Literature-Practical Clinical Insights and Many Unmet Needs on Diagnosis and Treatment.
Pharmaceuticals (Basel)
August 2024
Pulmonology Unit, Department of Medical Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy.
Article Synopsis
- This literature review examines the role of the gastrointestinal (GI) tract in sarcoidosis, which is a rare inflammatory disease that can be difficult to diagnose and treat due to overlapping symptoms with other GI disorders.* -
- GI sarcoidosis can impact any area of the gastrointestinal system, particularly the stomach and small intestine, leading to symptoms that range from mild discomfort to serious complications like obstruction or perforation.* -
- Current treatment options primarily involve corticosteroids, but their long-term effectiveness and safety are questionable, highlighting the urgent need for better diagnostic methods and standardized treatment protocols.*
Gastric signet-ring cell adenocarcinoma masquerading as sarcoidosis.
Lancet Oncol
April 2024
Department of Oncodermatology, Centre Léon Bérard, Lyon, France. Electronic address:
Novel Approach in Cardiac Sarcoidosis: A Case Report Highlighting Abatacept as a Promising Treatment Option.
Cureus
September 2023
Rheumatology, Louisiana State University Health Sciences Center, Shreveport, USA.
Cardiac sarcoidosis (CS) is a rare auto-immune disorder where immune cells form granulomas in the heart that may lead to potential arrhythmias and heart failure. Due to the low prevalence of CS, the management remains challenging, requiring a multidisciplinary approach. In addition to the management of the resulting arrhythmias and heart failure, corticosteroids and immunosuppressants are used as anti-inflammatories to prevent disease progression.
View Article and Find Full Text PDFGastric Sarcoidosis Flare After Years of Remission Following COVID Infection.
Dig Dis Sci
September 2023
Department of Pathology, City of Hope Medical Center, Duarte, CA, USA.
Dietary Implications of the Bidirectional Relationship between the Gut Microflora and Inflammatory Diseases with Special Emphasis on Irritable Bowel Disease: Current and Future Perspective.
Nutrients
June 2023
Laboratory of Animal Health, Food Hygiene and Quality, Department of Agriculture, University of Ioannina, 47100 Arta, Greece.
The immune system is vital for safeguarding the human body against infections and inflammatory diseases. The role of diet and meal patterns in modulating immune function is complex, and highlighting this topic is crucial for identifying potential ways to improve immune health. In Europe, the Mediterranean diet and Western diet are the most common dietary patterns, and gaining an understanding of how they affect immune function is essential for public health.
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